DRSC/TRiP Functional Genomics Resources

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Protein Alignment STK32C and Akt

DIOPT Version :10

Sequence 1:XP_011537990.1 Gene:STK32C / 282974 HGNCID:21332 Length:504 Species:Homo sapiens
Sequence 2:NP_732113.3 Gene:Akt / 41957 FlyBaseID:FBgn0010379 Length:611 Species:Drosophila melanogaster


Alignment Length:329 Identity:105/329 - (31%)
Similarity:169/329 - (51%) Gaps:33/329 - (10%)


- Green bases have known domain annotations that are detailed below.


Human    67 LASGLAARGTQTQSVLFGEVRLPLDGGVRGARKRMNFDHFQILRAIGKGSFGKPCALQVCIVQKR 131
            |:...:.:||...|           .||    |::..::|:.|:.:|||:|||     |.:.:::
  Fly   242 LSEQFSVQGTTCNS-----------SGV----KKVTLENFEFLKVLGKGTFGK-----VILCREK 286

Human   132 DTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDL 196
            .|.|:||:|.:.|:..|::|||.:...|..:|:...|.||::|.||||..:.:..|:..:.||:|
  Fly   287 ATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTNHPFLISLKYSFQTNDRLCFVMQYVNGGEL 351

Human   197 RYHLQQNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDFNIA-TIIK 260
            .:||.....|:||..|.|..|:..||.||..|.||:||:|.:|:|||:.||..:.||.:. ..|.
  Fly   352 FWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDIT 416

Human   261 DGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLV 325
            .|.......||..|:|||:...     ..|...||||..||:.||::.|..|:.....:.:.:|:
  Fly   417 YGRTTKTFCGTPEYLAPEVLDD-----NDYGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLI 476

Human   326 QLFSTVSVQYVPTWSKEMVALLRKLLTVNPEHRL----SSLQDVQAAPALAGVLWDHLSEKRVEP 386
            .:   ..|::....:.|...||..||..:|:.||    ..::::||.|..|.:.|..|..|::.|
  Fly   477 LV---EEVKFPRNITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPP 538

Human   387 GFVP 390
            .|.|
  Fly   539 PFKP 542

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
STK32CXP_011537990.1 STKc_Yank1 105..371 CDD:270730 91/270 (34%)
AktNP_732113.3 PH_PKB 105..214 CDD:269947
STKc_PKB 270..590 CDD:270723 96/286 (34%)
Blue background indicates that the domain is not in the aligned region.

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