Protein Alignment STK32C and dop

DIOPT Version :10

• Sequence 1: XP_011537990.1
• Gene: STK32C / 282974
• HGNCID: 21332
• Length: 504
• Species: Homo sapiens
• Sequence 2: NP_648778.1
• Gene: dop / 39686
• FlyBaseID: FBgn0267390
• Length: 2139
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 132/519 - (25%)
• Similarity: 221/519 - (42%)
• Gaps: 85/519 - (16%)

Human    12 GAGGAARGQPSRKELLLRHHLWSGPRCLSFPLGSLPASLLGLPGATSHRSCLSPNLASGLAARGT 76
            |:|.|...||              |:.......:.|:..|.:......:...|..:..|.:::..
  Fly   757 GSGTATPQQP--------------PQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVA 807

Human    77 QTQSVLFGEVRLPLDGGVRGARKRMNFDHFQILRAIGKGSFGKPCALQVCIVQKRDTEKMYAMKY 141
            ..:.:..|........|.:....:.|  .|.|::.|..|::|     .|.:|:.:.|.:.:|||.
  Fly   808 GAEGITGGSAATATGSGAQQPSPQEN--DFDIVKLISNGAYG-----AVYLVKHKTTRQRFAMKK 865

Human   142 MNKQQCIERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQF 206
            :||...|.|::|..||.|.:||...::.|:|:::.||:.::.:.:|::.:.|||....|:.....
  Fly   866 INKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPL 930

Human   207 SEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHAHLTDF--------NIATIIKDG- 262
            ..|..|.|..|..||::||....|:|||:||||:|:...||..||||        ::||.:.:|
  Fly   931 PADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGY 995

Human   263 -ERAT------ALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRPYDIHSSNA 320
             :..|      .:.||..|:|||:...     .||...|||||:|::.||.|.|..|:      .
  Fly   996 IDSETRQFSDKQVYGTPEYIAPEVILR-----QGYGKPVDWWSMGIILYEFLIGCVPF------F 1049

Human   321 VESLVQLFS-TVS--VQYVPT--WSKEMVA--LLRKLLTVNPEHRL---SSLQDVQAAPALAGVL 375
            .|:..:||: ||:  :::..:  |..:..|  ::.:||..||..||   |...:::......|:.
  Fly  1050 GETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMD 1114

Human   376 WDHLSEKRVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSRDSSQSENDYL 440
            |:.|..::.|  |||...  |.|.|...:..:                 .|.| .|....:.|..
  Fly  1115 WNSLLRQKAE--FVPQLS--HDDDTSYFDTRM-----------------DRYN-HDLGGEDTDDT 1157

Human   441 QDCLDAIQQDFVIFNREKLKRSQDLPREPLPAPESRDAAEPVEDEAERSALPMCGPICPSAGSG 504
            .|  ..:...|..:..:..|:.....|.  ..|.|.|.|:|. .....|:||......|:|..|
  Fly  1158 DD--TPVFGSFNSYTPQYRKQHYSWSRH--ATPTSTDGAKPT-GPPPLSSLPSRAQETPAATVG 1216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK32C	XP_011537990.1	STKc_Yank1	105..371	CDD:270730	90/291 (31%)
dop	NP_648778.1	DUF1908	344..702	CDD:462637
		STKc_MAST	834..1115	CDD:270760	91/296 (31%)
		PDZ_MAST	1502..1594	CDD:467189