Protein Alignment STK32C and S6k

DIOPT Version :9

• Sequence 1: XP_011537990.1
• Gene: STK32C / 282974
• HGNCID: 21332
• Length: 504
• Species: Homo sapiens
• Sequence 2: NP_001261450.1
• Gene: S6k / 38654
• FlyBaseID: FBgn0283472
• Length: 490
• Species: Drosophila melanogaster
• Alignment Length: 460
• Identity: 130/460 - (28%)
• Similarity: 208/460 - (45%)
• Gaps: 67/460 - (14%)

Human    63 LSPNLASGL--AARGTQT-----QSVLFGEVRL-PLDGGVRGARKRMNFDHFQILRAIGKGSFGK 119
            |.|.|...|  ...|.:|     ::|..|:::| |.|              |::.:.:|||.:||
  Fly    40 LEPELCINLHQDTEGQETIQLCEENVNPGKIKLGPKD--------------FELKKVLGKGGYGK 90

Human   120 PCALQVCIVQKRDTEKMYAMKYMNKQQCI-ERDEVRNVFRELEILQEIEHVFLVNLWYSFQDEED 183
              ..||.....||..|.:|||.:.|...: .:.:..:...|..||:.::|.|:|.|.|:||.:..
  Fly    91 --VFQVRKTAGRDANKYFAMKVLKKASIVTNQKDTAHTRAERNILEAVKHPFIVELVYAFQTDGK 153

Human   184 MFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRGQHIIHRDVKPDNILLDERGHA 248
            ::::::.|.||:|..||::...|.|||...|:.|:.|||.:|....||:||:||:|||||.:||.
  Fly   154 LYLILEYLSGGELFMHLEREGIFLEDTTCFYLSEIILALGHLHKLGIIYRDLKPENILLDAQGHV 218

Human   249 HLTDFNIA-TIIKDGERATALAGTKPYMAPEIFHSFVNGGTGYSFEVDWWSVGVMAYELLRGWRP 312
            .||||.:. ..|::|.......||..||||||...     :|:...|||||:|.:.:::|.|..|
  Fly   219 KLTDFGLCKEHIQEGIVTHTFCGTIEYMAPEILTR-----SGHGKAVDWWSLGALMFDMLTGVPP 278

Human   313 YDIHS-SNAVESLVQLFSTVSVQYVPTWSKEMVALLRKLLTVNPEHRLSSLQD----VQAAPALA 372
            :...: ...:|::::....:.....|    |...|:|:|:......||.|..:    ||..|...
  Fly   279 FTAENRKKTIETILKAKLNLPAYLTP----EARDLVRRLMKRQEPQRLGSGPEDAAAVQIHPFFK 339

Human   373 GVLWDHLSEKRVEPGFVPNKGRLHCDPTFELEEMILESRPLHKKKKRLAKNKSRDNSRDSSQSEN 437
            .|.||.:..:|:||...|               ::.....:.:...|..:....|:..|::.||:
  Fly   340 HVNWDDVLARRLEPPIKP---------------LLRSEDDVSQFDTRFTRQIPVDSPDDTTLSES 389

Human   438 DYLQDCLDAIQQDFVIFNREKLKRSQDLPR-EPLPAPESRDAAEPVEDEAERSALPMC--GPICP 499
            ..|      |.|.|.......|   :|:.| ..:||...|.....:.|.:.|...|..  |...|
  Fly   390 ANL------IFQGFTYVAPSIL---EDMHRANRMPARSPRRTPRQLPDSSFRLQFPSANVGANAP 445

Human   500 SAGSG 504
            .|..|
  Fly   446 LAMHG 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK32C	XP_011537990.1	STKc_Yank1	105..371	CDD:270730	90/272 (33%)
		S_TKc	106..366	CDD:214567	87/266 (33%)
S6k	NP_001261450.1	PTZ00263	76..397	CDD:140289	106/366 (29%)
		STKc_p70S6K	81..402	CDD:270736	105/352 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810