Protein Alignment ZNF311 and Gm14308

DIOPT Version :10

• Sequence 1: XP_005249076.1
• Gene: ZNF311 / 282890
• HGNCID: 13847
• Length: 699
• Species: Homo sapiens
• Sequence 2: NP_001092819.1
• Gene: Gm14308 / 100043381
• MGIID: 3782921
• Length: 498
• Species: Mus musculus
• Alignment Length: 568
• Identity: 247/568 - (43%)
• Similarity: 316/568 - (55%)
• Gaps: 84/568 - (14%)

Human    97 VTFEDVAVNFTNREWQCLTYAQRHLYKDVMLENYGNMVSLGFPFPKPPLISHLEREVDPCVQDPQ 161
            ||::||.||||..||..|..:|:.|||.||||.|.|:.::|:.:.:..:..|.:      .....
Mouse     4 VTYDDVHVNFTQDEWALLDPSQKSLYKGVMLETYKNLTAIGYIWEEHTIEDHFQ------TSRSH 62

Human   162 DRESLSCSYPVSADKMWPENEKASSQQEIFENGEAYWMKFNSLLKVDSRDPKVREVCVQDVKLEN 226
            .|...|||              |....|..:.|:|:
Mouse    63 GRHERSCS--------------AEQPSEFIQCGKAF----------------------------- 84

Human   227 QWETSIREKLREEKEGSEEVTCKKGKNQKVLSKNLNPNSKHSQCNKVLIAQKLHECARCGKNFSW 291
                                ..:.|:.:..:..|               .:|.|:|.:|||:|..
Mouse    85 --------------------AYESGRQRHQIKHN---------------GEKHHDCNQCGKDFRT 114

Human   292 HSDLILHEQIHSGEKPHVCNECGKAFKTRNQLSMHRIIHTGEKPFNCTQCGKAFNSRSALCRHKK 356
            .:.|.:|::.|:||||:.|.:|||.|.....|.:|...|.|||.:.|.||||||..|..|..||:
Mouse   115 WNVLQIHKRTHTGEKPYDCKQCGKVFARSCHLQIHNRTHAGEKQYECNQCGKAFKRRINLQIHKR 179

Human   357 THSGEKPHECRDCGKAFKTRNRLCMHQLIHTGEKPYKCNCCGKAFQFKHSLTIHGRIHTGEKPYE 421
            ||:||||:||..|||||.:...|..|:..|||||||:|..|||||.....|.||.|.||||||||
Mouse   180 THTGEKPYECNQCGKAFASSGELQKHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYE 244

Human   422 CEECGKAFSGSSDLTKHIRIHTGERPYECSKCGRAFSRSSDLSKHKRIHTREKHYGCPQCGKDFS 486
            |.:|||||:.|.||.||.|.||||:||||.:||:||:.||.|.||:|.||.:|.|.|.||||.|:
Mouse   245 CNQCGKAFARSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHKHERTHTGDKPYECKQCGKAFA 309

Human   487 IKAELTKHRRIHTEEKRYRCEECGKAFRHNCKRRAHEREHTGEKPYQCRDCGKTFQDKHCLTIHQ 551
            :...|..|:|.||.:|.|.|::|||||......:.|:|.|||||||:|:.|||.|.....|.||:
Mouse   310 VIYTLQMHKRTHTGDKPYECKQCGKAFAVIYTLQMHKRTHTGEKPYKCKQCGKAFARSCHLRIHK 374

Human   552 RIHTGEKPYKCLECGKAFSGKSNLTNHRRIHTGEKPHKCEVCGMAFHHSSVLRQHKRIHTGEKPY 616
            |.|||||||:|.:|||||:..|.|..|.|.||||||::|..||.||....||:.|||.|||||||
Mouse   375 RTHTGEKPYECNQCGKAFAESSTLQIHNRTHTGEKPYECNQCGKAFITRRVLQIHKRTHTGEKPY 439

Human   617 TCSECGTSFRQGSALIGHKRVHTGEKPYECEECGKAFRVSSNLTGHKK 664
            .|::||.:|.:...|..|||.|||||||||..|||||..||:|..||:
Mouse   440 ECNQCGKAFARSCDLQKHKRTHTGEKPYECNHCGKAFAQSSSLRIHKR 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF311	XP_005249076.1	KRAB	97..157	CDD:214630	23/59 (39%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		COG5048	306..>633	CDD:227381	180/326 (55%)
		C2H2 Zn finger	310..330	CDD:275368	7/19 (37%)
		C2H2 Zn finger	338..358	CDD:275368	11/19 (58%)
		C2H2 Zn finger	366..386	CDD:275368	8/19 (42%)
		C2H2 Zn finger	394..414	CDD:275368	10/19 (53%)
		C2H2 Zn finger	422..442	CDD:275368	12/19 (63%)
		C2H2 Zn finger	450..470	CDD:275368	11/19 (58%)
		C2H2 Zn finger	478..498	CDD:275368	9/19 (47%)
		C2H2 Zn finger	506..526	CDD:275368	8/19 (42%)
		C2H2 Zn finger	534..554	CDD:275368	9/19 (47%)
		C2H2 Zn finger	562..582	CDD:275368	10/19 (53%)
		C2H2 Zn finger	590..610	CDD:275368	10/19 (53%)
		C2H2 Zn finger	618..638	CDD:275368	8/19 (42%)
		zf-H2C2_2	634..653	CDD:463886	15/18 (83%)
		C2H2 Zn finger	646..664	CDD:275368	10/17 (59%)
Gm14308	NP_001092819.1	KRAB	3..44	CDD:460171	21/39 (54%)
		COG5048	74..486	CDD:227381	217/475 (46%)
		C2H2 Zn finger	79..97	CDD:275368	3/66 (5%)
		C2H2 Zn finger	105..125	CDD:275368	7/19 (37%)
		C2H2 Zn finger	133..153	CDD:275368	7/19 (37%)
		C2H2 Zn finger	161..181	CDD:275368	11/19 (58%)
		C2H2 Zn finger	189..209	CDD:275368	8/19 (42%)
		C2H2 Zn finger	217..237	CDD:275368	10/19 (53%)
		C2H2 Zn finger	245..265	CDD:275368	12/19 (63%)
		C2H2 Zn finger	273..293	CDD:275368	11/19 (58%)
		C2H2 Zn finger	301..321	CDD:275368	9/19 (47%)
		C2H2 Zn finger	329..349	CDD:275368	8/19 (42%)
		C2H2 Zn finger	357..377	CDD:275368	9/19 (47%)
		C2H2 Zn finger	385..405	CDD:275368	10/19 (53%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		C2H2 Zn finger	469..488	CDD:275368	11/19 (58%)