DRSC/TRiP Functional Genomics Resources

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Protein Alignment POC1B and pop3

DIOPT Version :9

Sequence 1:NP_758440.1 Gene:POC1B / 282809 HGNCID:30836 Length:478 Species:Homo sapiens
Sequence 2:NP_595682.1 Gene:pop3 / 2540645 PomBaseID:SPBC21B10.05c Length:314 Species:Schizosaccharomyces pombe


Alignment Length:304 Identity:73/304 - (24%)
Similarity:113/304 - (37%) Gaps:78/304 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    65 SVQFSP-HGNLLASASRDRTVRLW-----------------------IPDKRGKF---------- 95
            |||:.| |..||.|:..|.|:|.|                       .|||  ||          
pombe     2 SVQYPPQHSVLLVSSGYDHTIRFWEALSGICSRTIQHADSQVNRLCISPDK--KFLAAAGNPHVR 64

Human    96 ------------SEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLYRHTHWVR 148
                        ..|:.||..|.::.|..||::|||:|||.::|||.| |...:...|.|...|.
pombe    65 LYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDM-RAPSVQRNYDHKSPVN 128

Human   149 CAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNF--SDSVGFANFVDFNPSGTCIASAGSDQTVK 211
            .....|:...::||.:...::.||.....|.:..  .:.|..:: :.....|:.:.:..:.....
pombe   129 DLLIHPNQGELLSCDQSGRVRAWDLGENSCTHELIPEEDVPMSS-ITVGSDGSMLIAGNNKGNCY 192

Human   212 VWDVRVNKLLQH-----------YQVHSGGVNCISFHPSGNYLITASSDGTLKILD------LLE 259
            ||     ::|.|           :|.|...:......|...:|.|.|:|.|:.|..      :||
pombe   193 VW-----RMLNHQGASLLQPVVKFQAHQRYITRCVLSPDVKHLATCSADATVNIWSTEDMSFMLE 252

Human   260 GRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTNFDE 303
            .|    ||||...|:..:||.......:..:|....||..:..|
pombe   253 RR----LQGHQRWVWDCAFSADSTYLVTASSDHVARLWELSSGE 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
POC1BNP_758440.1 WD40 10..298 CDD:238121 71/297 (24%)
WD 1 16..55
WD40 repeat 21..58 CDD:293791
WD 2 58..99 17/79 (22%)
WD40 repeat 63..100 CDD:293791 18/80 (23%)
WD 3 101..139 17/37 (46%)
WD40 repeat 106..142 CDD:293791 14/35 (40%)
WD 4 142..181 8/38 (21%)
WD40 repeat 147..182 CDD:293791 7/34 (21%)
WD 5 183..223 5/39 (13%)
WD40 repeat 190..225 CDD:293791 5/45 (11%)
WD 6 226..265 11/44 (25%)
WD40 repeat 231..267 CDD:293791 10/41 (24%)
WD 7 268..307 9/36 (25%)
WD40 repeat 273..299 CDD:293791 6/25 (24%)
pop3NP_595682.1 WD40 1..287 CDD:238121 71/297 (24%)
WD40 9..>301 CDD:225201 69/297 (23%)
WD40 repeat 44..81 CDD:293791 6/38 (16%)
WD40 repeat 86..122 CDD:293791 15/36 (42%)
WD40 repeat 128..163 CDD:293791 6/34 (18%)
WD40 repeat 170..212 CDD:293791 5/47 (11%)
WD40 repeat 218..256 CDD:293791 10/41 (24%)
WD40 repeat 262..286 CDD:293791 4/23 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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