Protein Alignment GPR3 and ser-2

DIOPT Version :9

• Sequence 1: NP_005272.1
• Gene: GPR3 / 2827
• HGNCID: 4484
• Length: 330
• Species: Homo sapiens
• Sequence 2: NP_001024339.1
• Gene: ser-2 / 182110
• WormBaseID: WBGene00004777
• Length: 455
• Species: Caenorhabditis elegans
• Alignment Length: 444
• Identity: 81/444 - (18%)
• Similarity: 147/444 - (33%)
• Gaps: 178/444 - (40%)

Human    16 SGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTL---------VSCENALVVAIIVGTPAF 71
            |..|:.:::.|.:.|.....|   |.....|..:.||:         |.....:|||:....|..
 Worm    28 SSAVSTTTLPPLDIPMTSMKP---PSIIPTVELVLGTITYLVIIAMTVVGNTLVVVAVFSYRPLK 89

Human    72 RAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAF---------TASIGSL 127
            :...:.|| |||.:||...:.::......|..|..    .|:||....|         |:||.:|
 Worm    90 KVQNYFLV-SLAASDLAVAIFVMPLHVVTFLAGGK----WLLGVTVCQFFTTADILLCTSSILNL 149

Human   128 LAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWN----------CLDGLT 182
            .||.:|||.:::|.:.|..:.|.....:::.:||..::.:.:.|::.||          |  ||:
 Worm   150 CAIALDRYWAIHNPINYAQKRTTKFVCIVIVIVWILSMLISVPPIIGWNNWQENMMEDSC--GLS 212

Human   183 TCGVVYPLSKNHLVVLAIA--FFMVFGIMLQLYAQI----------------------------- 216
            |        :...||.:.|  ||:...:|:.:|.:|
 Worm   213 T--------EKAFVVFSAAGSFFLPLLVMVVVYVKIFISARQRIRTNRGRSALMRIQNAEGDDDY 269

Human   217 ---------------------------------------------------------------CR 218
                                                                           |:
 Worm   270 RKMSIKRASVESARTSSRVGEKTPLVIADGQTTVTTLAAHSTDGGSLPKDETTKHMKYHNNGSCK 334

Human   219 I----------------VCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTV-- 265
            :                |.|..::|::.:.          ::...|:||::..|:.|||||.|
 Worm   335 VKVKDVKEDEGNPNPTAVLRKREKISVAKE----------KRAAKTIAVIIFVFSFCWLPFFVAY 389

Human   266 ----YCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCC 313
                :|.....|:  ...:|:|..:    ||.:||.:|...|.:.::....:.|
 Worm   390 VIRPFCETCKLHAKVEQAFTWLGYI----NSSLNPFLYGILNLEFRRAFKKILC 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPR3	NP_005272.1	7tm_GPCRs	41..308	CDD:391938	74/412 (18%)
		TM helix 1	43..67	CDD:341315	7/32 (22%)
		TM helix 2	76..97	CDD:341315	7/20 (35%)
		TM helix 3	110..132	CDD:341315	10/30 (33%)
		TM helix 4	155..171	CDD:341315	2/15 (13%)
		TM helix 5	191..214	CDD:341315	6/24 (25%)
		TM helix 6	243..268	CDD:341315	10/30 (33%)
		TM helix 7	276..301	CDD:341315	7/24 (29%)
ser-2	NP_001024339.1	7tm_1	74..423	CDD:278431	68/377 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910