DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment f7i and flz

DIOPT Version :9

Sequence 1:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	273	Identity:	84/273 - (30%)
Similarity:	119/273 - (43%)	Gaps:	41/273 - (15%)

- Green bases have known domain annotations that are detailed below.

Zfish   172 CGKIPVQKNTSQNQFLGGIHCPRGHCPWQVLIDYN------GESVCGGALLEGPWLITAAHCVHQ 230
            ||   |:.:....:.:||.....|..|||||:..:      .::.|||.|:...::||||||
  Fly  1438 CG---VRPHVKSGRIVGGKGSTFGAYPWQVLVRESTWLGLFTKNKCGGVLITSRYVITAAHC--- 1496

Zfish   231 KDTRFLK---AVTGEHDL--DVLDGSEEPYEVSAVFIHPNYDPETLDSDLALLRLRVPVQRSLYA 290
             ...||.   ||.||.|:  |:.........|..|.:|..|||.|.::|||||.|..|||...:.
  Fly  1497 -QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRVIVHRQYDPATFENDLALLELDSPVQFDTHI 1560

Zfish   291 VPICLPTPQLARSELWAARFHTLSGWGTRTAGHNLRREKGLKGPASGTLQRLAVPLLPAAQC--- 352
            ||||:|.....    :..|..|::|||....|          |.....||.:.||::..:.|
  Fly  1561 VPICMPNDVAD----FTGRMATVTGWGRLKYG----------GGVPSVLQEVQVPIIENSVCQEM 1611

Zfish   353 -----GNANTTANMFCAGYTEGDHASCRGHDGSPLVTRYGETSF-LTGVVSWGRGCGPPGYYWIY 411
                 .|.....:..||||..|...||.|..|.|||.:..:..: |.|.||.|..|..|....:|
  Fly  1612 FHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGTVSHGIKCAAPYLPGVY 1676

Zfish   412 TKVENFLIWMDTV 424
            .:...:..|:.::
  Fly  1677 MRTTFYKPWLRSI 1689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
f7i	NP_775335.1	GLA	20..82	CDD:214503
		EGF_CA	<91..120	CDD:238011
		FXa_inhibition	129..164	CDD:291342
		Tryp_SPc	188..420	CDD:214473	80/251 (32%)
		Tryp_SPc	188..420	CDD:238113	80/251 (32%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	81/257 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000