Protein Alignment SLCO3A1 and Oatp58Da

DIOPT Version :9

• Sequence 1: NP_037404.2
• Gene: SLCO3A1 / 28232
• HGNCID: 10952
• Length: 710
• Species: Homo sapiens
• Sequence 2: NP_611657.2
• Gene: Oatp58Da / 37543
• FlyBaseID: FBgn0050277
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 183/662 - (27%)
• Similarity: 291/662 - (43%)
• Gaps: 121/662 - (18%)

Human    58 AYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALL 122
            ||....:||||:|:.:.:...|:|:...:|..:.....:.|:....||||.:|.|.:.:....||
  Fly    84 AYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLL 148

Human   123 SALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTATN------------- 174
            ::...||     |.|||        |........|..         |.|.||
  Fly   149 TSSLHFL-----YGAGE--------DALQLTREFGQV---------NETLTNQERDKKLCQPTAG 191

Human   175 ----------MMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACG 229
                      :..:.|..||::.|:|......||::|:||:..:..:...:.:...:.:.|||.|
  Fly   192 GCVQEEVGLWVPQVFLFAAQLISGVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIG 256

Human   230 FILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSE 294
            :.|.:.|.::|::    .|....|..:||||:||||.|:|:..|:...|::|:|.||:.|
  Fly   257 YSLAAVCLRLYIE----PTLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQL----- 312

Human   295 PAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAAC 359
            |:....:..|.:.|.::..|.|.               :.|..:.|..|.|..|.|:....:|:.
  Fly   313 PSARKRRLQLKQDERKQSLPLNE---------------RSLADMMKTVKKLSKNKVYVYNTMASI 362

Human   360 MEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMA 424
            :.......:..|..||:|.|:..:.:.|....|..|:..:..||.:.|.::.|...||.......
  Fly   363 LYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWN 427

Human   425 MLVNLVSTA---CYVSFLFLGCDTGPVAG--VTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTP 484
            .:|:.|:.|   |||:   :||:......  .|:..|||            |:.:|.|....:.|
  Fly   428 AIVDFVTVAGILCYVA---IGCEGSDRLNTLTTLSAGNS------------CSASCHCDYVHYAP 477

Human   485 VCGADGITYLSACFAGCNS--------TNLTGCAC-----LTTVPAENATVVPGKCPSPGCQEAF 536
            ||.||.||::|||.|||:.        |..|||.|     |.:.| |:...|.|.|| ..|...|
  Fly   478 VCSADNITFISACHAGCSERTKDALGRTIYTGCECLGSSSLNSEP-ESQFAVDGTCP-VDCFNEF 540

Human   537 LTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTC 601
            |.||.|||...|:||.:::.::::.:|.:.|:.|::|||:..:...||||||.|:.||..||:.|
  Fly   541 LIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYC 605

Human   602 LFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFI---LYTTTWQCLRKNYKRY-------- 655
            |.|...|..:|.|.|||....||   ::.::...|.|:   |....|. ..||.|.:
  Fly   606 LVWGKTCSNKGNCWLYDTKSMRY---ALNLSAAFFIFLGGFLNIAVWY-HAKNLKIFDEEESSPK 666

Human   656 --IKNHEGGLST 665
              :||.|..:.|
  Fly   667 DSLKNKEVEMKT 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLCO3A1	NP_037404.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		OATP	41..619	CDD:281175	169/601 (28%)
		MFS	47..>286	CDD:119392	64/250 (26%)
		KAZAL_SLC21	467..511	CDD:238650	20/51 (39%)
Oatp58Da	NP_611657.2	OATP	67..626	CDD:281175	170/604 (28%)
		MFS	69..>425	CDD:119392	93/386 (24%)
		KAZAL_SLC21	462..514	CDD:238650	23/63 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145465
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750