Protein Alignment GPM6A and gpm6ab

DIOPT Version :10

• Sequence 1: NP_005268.1
• Gene: GPM6A / 2823
• HGNCID: 4460
• Length: 278
• Species: Homo sapiens
• Sequence 2: XP_005160038.1
• Gene: gpm6ab / 407734
• ZFINID: ZDB-GENE-030710-8
• Length: 285
• Species: Danio rerio
• Alignment Length: 285
• Identity: 242/285 - (84%)
• Similarity: 262/285 - (91%)
• Gaps: 7/285 - (2%)

Human     1 MEENMEEGQTQKGCFECCIKCLGGIPYASLIATILLYAGVALFCGCGHEALSGTVNILQTYFEMA 65
            ||||||||||||||.|||:|||.||||||||||||||||||||||||||||||||.||||||::.
Zfish     1 MEENMEEGQTQKGCSECCLKCLSGIPYASLIATILLYAGVALFCGCGHEALSGTVTILQTYFDVV 65

Human    66 RTAGDTLDVFTMIDIFKYVIYGIAAAFFVYGILLMVEGFFTTGAIKDLYGDFKITTCGRCVSAWF 130
            |:..|.||||||||||||||||:||||||||||||||||||||||:|||||||||||||||||||
Zfish    66 RSPVDALDVFTMIDIFKYVIYGVAAAFFVYGILLMVEGFFTTGAIRDLYGDFKITTCGRCVSAWF 130

Human   131 IMLTYLFMLAWLGVTAFTSLPVYMYFNLWTICRNTTLVEG-------ANLCLDLRQFGIVTIGEE 188
            |||||:||||||||||||||||:||||:|..|:|.||:||       ||||.||||:|||:||||
Zfish   131 IMLTYIFMLAWLGVTAFTSLPVFMYFNIWNTCQNMTLLEGSLSSANSANLCFDLRQYGIVSIGEE 195

Human   189 KKICTVSENFLRMCESTELNMTFHLFIVALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYED 253
            |::|..:|||.:||||.||::|||||:.|||||||||||||||||||||||||||||||||||||
Zfish   196 KRLCADNENFKKMCESNELDLTFHLFVCALAGAGAAVIAMVHYLMVLSANWAYVKDACRMQKYED 260

Human   254 IKSKEEQELHDIHSTRSKERLNAYT 278
            |||||||||||||||||||||||||
Zfish   261 IKSKEEQELHDIHSTRSKERLNAYT 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPM6A	NP_005268.1	Myelin_PLP	15..247	CDD:460144	195/238 (82%)
gpm6ab	XP_005160038.1	Myelin_PLP	15..254	CDD:460144	195/238 (82%)