Protein Alignment GPD1 and Gpdh1

DIOPT Version :10

• Sequence 1: NP_005267.2
• Gene: GPD1 / 2819
• HGNCID: 4455
• Length: 349
• Species: Homo sapiens
• Sequence 2: NP_476565.1
• Gene: Gpdh1 / 33824
• FlyBaseID: FBgn0001128
• Length: 360
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 234/352 - (66%)
• Similarity: 275/352 - (78%)
• Gaps: 5/352 - (1%)

Human     1 MASK-KVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYL 64
            ||.| .||||||||||||||||||.|||.|.:|:.||||:|:||.|.|||||||||..|||||||
  Fly     1 MADKVNVCIVGSGNWGSAIAKIVGANAAALPEFEERVTMFVYEELIDGKKLTEIINETHENVKYL 65

Human    65 PGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVD--EGPN 127
            .|||||||||||||:|:||::|||||||||||||...|.||.|.:|.||..||||||.|  || .
  Fly    66 KGHKLPPNVVAVPDLVEAAKNADILIFVVPHQFIPNFCKQLLGKIKPNAIAISLIKGFDKAEG-G 129

Human   128 GLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQ 192
            |:.|||.:|...|.||.:||||||:|:|||:..||||||||.|...|::|::|.|..:||:.||.
  Fly   130 GIDLISHIITRHLKIPCAVLMGANLANEVAEGNFCETTIGCTDKKYGKVLRDLFQANHFRVVVVD 194

Human   193 EVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGPVSSATFLESCG 257
            :.|.||:||||||:||.||||.|||..|||||||||||||||||.|..:|..|...| ||.||||
  Fly   195 DADAVEVCGALKNIVACGAGFVDGLKLGDNTKAAVIRLGLMEMIRFVDVFYPGSKLS-TFFESCG 258

Human   258 VADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLF 322
            ||||||||||||||:|:|||..:||:||:||||:|||||||||.||.|:..:|::|||.||||||
  Fly   259 VADLITTCYGGRNRRVSEAFVTSGKTIEELEKEMLNGQKLQGPPTAEEVNYMLKNKGLEDKFPLF 323

Human   323 MAVYKVCYEGQPVGEFIHCLQNHPEHM 349
            .|::|:|.......:.|.|::||||||
  Fly   324 TAIHKICTNQLKPNDLIDCIRNHPEHM 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPD1	NP_005267.2	glycerol3P_DH	5..342	CDD:274551	224/338 (66%)
Gpdh1	NP_476565.1	glycerol3P_DH	6..343	CDD:274551	224/338 (66%)