DRSC/TRiP Functional Genomics Resources

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Protein Alignment GP1BA and Toll-7

DIOPT Version :9

Sequence 1:NP_000164.5 Gene:GP1BA / 2811 HGNCID:4439 Length:652 Species:Homo sapiens
Sequence 2:NP_523797.1 Gene:Toll-7 / 37272 FlyBaseID:FBgn0034476 Length:1446 Species:Drosophila melanogaster


Alignment Length:181 Identity:60/181 - (33%)
Similarity:81/181 - (44%) Gaps:16/181 - (8%)


- Green bases have known domain annotations that are detailed below.


Human    36 RNLTALPPDLP--KDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTKLQVDGTLPV---- 94
            |.|...|..|.  |..|.|.|.:|.|.......|.|...|..|||.|..:...:..|...:    
  Fly   176 RTLELFPDSLGGLKQLTDLDLGDNNLRQLPSGFLCPVGNLQVLNLTRNRIRTAEQMGFADMNCGA 240

Human    95 --------LGTLDLSHNQLQSLPLLG--QTLPALTVLDVSFNRLTSLPLGALRGLGELQELYLKG 149
                    |..||.|||:|:|:....  ..|..|..|::::|.|:.|...||.||..|:.:.|..
  Fly   241 GSGSAGSELQVLDASHNELRSISESWGISRLRRLQHLNLAYNNLSELSGEALAGLASLRIVNLSN 305

Human   150 NELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 200
            |.|:|||.||...:.:|.::.|..|.|.|||.||.:.||.|..:.|..|.|
  Fly   306 NHLETLPEGLFAGSKELREIHLQQNELYELPKGLFHRLEQLLVVDLSGNQL 356

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GP1BANP_000164.5 LRRNT 19..50 CDD:214470 5/15 (33%)
leucine-rich repeat 30..48 CDD:275380 4/13 (31%)
LRR 1 48..68 5/19 (26%)
leucine-rich repeat 49..72 CDD:275380 7/22 (32%)
LRR_RI <51..200 CDD:238064 53/162 (33%)
LRR_8 71..128 CDD:290566 18/70 (26%)
LRR 2 72..93 6/20 (30%)
leucine-rich repeat 73..94 CDD:275380 6/20 (30%)
LRR 3 94..115 8/34 (24%)
leucine-rich repeat 95..117 CDD:275380 9/23 (39%)
LRR_8 116..176 CDD:290566 21/59 (36%)
LRR 4 117..137 6/19 (32%)
leucine-rich repeat 118..141 CDD:275380 9/22 (41%)
LRR 5 141..162 9/20 (45%)
leucine-rich repeat 142..165 CDD:275380 9/22 (41%)
LRR_8 164..222 CDD:290566 15/37 (41%)
LRR 6 165..186 9/20 (45%)
leucine-rich repeat 166..189 CDD:275380 10/22 (45%)
LRR 7 189..210 4/12 (33%)
leucine-rich repeat 190..210 CDD:275380 4/11 (36%)
leucine-rich repeat 213..225 CDD:275378
LRRCT 221..281 CDD:214507
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 336..459
Toll-7NP_523797.1 LRR_8 135..201 CDD:290566 9/24 (38%)
leucine-rich repeat 136..159 CDD:275380
leucine-rich repeat 160..190 CDD:275380 4/13 (31%)
LRR_8 189..259 CDD:290566 20/69 (29%)
leucine-rich repeat 191..214 CDD:275380 7/22 (32%)
leucine-rich repeat 215..248 CDD:275380 6/32 (19%)
LRR_RI 247..501 CDD:238064 42/110 (38%)
LRR_8 247..308 CDD:290566 21/60 (35%)
leucine-rich repeat 249..273 CDD:275380 9/23 (39%)
leucine-rich repeat 274..297 CDD:275380 9/22 (41%)
LRR_8 297..356 CDD:290566 23/58 (40%)
leucine-rich repeat 298..321 CDD:275380 9/22 (41%)
leucine-rich repeat 322..345 CDD:275380 10/22 (45%)
LRR_8 345..406 CDD:290566 4/12 (33%)
leucine-rich repeat 346..371 CDD:275380 4/11 (36%)
leucine-rich repeat 372..395 CDD:275380
leucine-rich repeat 396..419 CDD:275380
LRR_8 419..478 CDD:290566
leucine-rich repeat 420..443 CDD:275380
leucine-rich repeat 444..467 CDD:275380
LRR_RI 466..622 CDD:238064
leucine-rich repeat 468..488 CDD:275380
LRR_8 491..549 CDD:290566
leucine-rich repeat 491..514 CDD:275380
leucine-rich repeat 515..536 CDD:275380
leucine-rich repeat 539..562 CDD:275380
leucine-rich repeat 563..585 CDD:275380
leucine-rich repeat 586..626 CDD:275380
leucine-rich repeat 627..653 CDD:275380
LRRCT 716..772 CDD:214507
LRRNT 796..830 CDD:214470
leucine-rich repeat 812..829 CDD:275380
leucine-rich repeat 833..854 CDD:275380
LRR_8 853..913 CDD:290566
leucine-rich repeat 855..878 CDD:275380
LRR_4 878..918 CDD:289563
leucine-rich repeat 879..902 CDD:275380
leucine-rich repeat 903..926 CDD:275380
leucine-rich repeat 927..953 CDD:275380
TIR 1098..1235 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24373
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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