DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atp5o and ATPsynO

DIOPT Version :9

Sequence 1:	NP_613063.1	Gene:	Atp5o / 28080	MGIID:	106341	Length:	213	Species:	Mus musculus
Sequence 2:	NP_524358.2	Gene:	ATPsynO / 41845	FlyBaseID:	FBgn0016691	Length:	209	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	94/196 - (47%)
Similarity:	132/196 - (67%)	Gaps:	7/196 - (3%)

- Green bases have known domain annotations that are detailed below.

Mouse     9 LSRQVRSFSTSVVRPFAKLVRPPVQVYGIEGRYATALYSAASKEKKLDQVEKELLRVGQLLK-DP 72
            |||.:.|.:....      |:|||||:|:||||||||||||||..:||||||:|..:...:: |.
  Fly    10 LSRTLSSAAAQAT------VKPPVQVFGLEGRYATALYSAASKLSQLDQVEKDLTALQATIRSDK 68

Mouse    73 KVSLAVLNPYIKRTVKVKSLNDITKREKFSPLTANLMNLLAENGRLGNTQGIISAFSTIMSVHRG 137
            |:...|.:|.|.:.|...:|.:.:::.:|:|.|.||:.|||:||||.....:|:|:.|||:.|||
  Fly    69 KLREYVTSPIINKKVMATALKEASEKLRFAPATVNLLGLLADNGRLKKLDTVINAYKTIMAAHRG 133

Mouse   138 EVPCTVTTASPLDDAVLSELKTVLKSFLSPNQILKLEIKTDPSIMGGMIVRIGEKYVDMSAKSKI 202
            ||.|.|.||.|||.:...:|:..|||||..|:.||:..:.||||:||:||.||:||||||..:|:
  Fly   134 EVVCEVVTAKPLDASQSKQLEGALKSFLKGNESLKITSRVDPSIIGGLIVSIGDKYVDMSIATKV 198

Mouse   203 Q 203
            :
  Fly   199 K 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atp5o	NP_613063.1	OSCP	37..209	CDD:306679	83/168 (49%)
ATPsynO	NP_524358.2	OSCP	32..199	CDD:278635	83/166 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850711
Domainoid	1	1.000	160	1.000	Domainoid score	I4055
eggNOG	1	0.900	-	-		E1_COG0712
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1283
Inparanoid	1	1.050	177	1.000	Inparanoid score	I4030
Isobase	1	0.950	-	0	Normalized mean entropy	S1100
OMA	1	1.010	-	-		QHG57719
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004090
OrthoInspector	1	1.000	-	-		oto92530
orthoMCL	1	0.900	-	-		OOG6_101031
Panther	1	1.100	-	-	LDO	PTHR11910
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R121
SonicParanoid	1	1.000	-	-		X3931
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740