Protein Alignment GOT1 and Got1

DIOPT Version :9

• Sequence 1: NP_002070.1
• Gene: GOT1 / 2805
• HGNCID: 4432
• Length: 413
• Species: Homo sapiens
• Sequence 2: NP_725534.1
• Gene: Got1 / 36782
• FlyBaseID: FBgn0001124
• Length: 437
• Species: Drosophila melanogaster
• Alignment Length: 406
• Identity: 229/406 - (56%)
• Similarity: 294/406 - (72%)
• Gaps: 5/406 - (1%)

Human     5 SVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNH 69
            |::|:||:...:.||.||..|::|.:|.||||.|||||||...|||||||:|.|..||:|..:||
  Fly    23 SIYADVPKGPAIEVFALTQAFKDDSNPNKVNLSVGAYRTDAGVPWVLPVVRKTEISIASDEQVNH 87

Human    70 EYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPV 134
            ||||:.||..|.:.|:.|.||.||||:||.|..|||::.||||||:.||||    :...|:|. |
  Fly    88 EYLPVTGLETFTNAATELVLGADSPAIKENRAFGVQTISGTGALRVAADFL----HTQLNRNV-V 147

Human   135 YVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGI 199
            |.|:||||||:.:|..|||..::||||||..||.||.:..|.||.:||..::::|||||||||||
  Fly   148 YYSNPTWENHHKIFCDAGFTTVKSYRYWDQNKRELDFKNMLADLNDAPPGAVIILHACAHNPTGI 212

Human   200 DPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLY 264
            |||.|||.::|.:|:.:.|||.|||||||||||:.:|||||.||||..|||.|..|||:||||||
  Fly   213 DPTQEQWTELADLMEKKKLFPLFDSAYQGFASGDPDRDAWAARYFVQRGFELFICQSFAKNFGLY 277

Human   265 NERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMAD 329
            .||.|||.||.|...:...|.||:..::|..:|||||.|||||:..|:.|||.:||..:::.|:.
  Fly   278 CERTGNLAVVQKNGATKAAVHSQLTLLIRGQYSNPPAYGARIVSKVLNTPELRKEWMASIQAMSS 342

Human   330 RILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLT 394
            ||..||:.||.:|.||.|||||:||.:||||||:||||...|..|:::.|||||.:|||::|||.
  Fly   343 RIREMRTALRDKLVALGTPGTWDHIVNQIGMFSYTGLNESHVRVLIDQYHIYLLKTGRISMSGLN 407

Human   395 TKNLDYVATSIHEAVT 410
            ..|::|||.:||.|||
  Fly   408 KGNVEYVAKAIHAAVT 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GOT1	NP_002070.1	PTZ00376	5..412	CDD:240390	229/406 (56%)
Got1	NP_725534.1	PTZ00376	21..423	CDD:240390	227/404 (56%)
		Aminotran_1_2	49..418	CDD:278580	214/373 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143146
Domainoid	1	1.000	436	1.000	Domainoid score	I567
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1571
Inparanoid	1	1.050	468	1.000	Inparanoid score	I1532
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62835
OrthoDB	1	1.010	-	-		D1104596at2759
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	1	1.000	-	-		oto89204
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	1	1.100	-	-	LDO	PTHR11879
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2019
SonicParanoid	1	1.000	-	-		X428
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.800