Protein Alignment GOT1 and Got2

DIOPT Version :10

• Sequence 1: NP_002070.1
• Gene: GOT1 / 2805
• HGNCID: 4432
• Length: 413
• Species: Homo sapiens
• Sequence 2: NP_722745.1
• Gene: Got2 / 33373
• FlyBaseID: FBgn0001125
• Length: 431
• Species: Drosophila melanogaster
• Alignment Length: 405
• Identity: 192/405 - (47%)
• Similarity: 279/405 - (68%)
• Gaps: 7/405 - (1%)

Human     7 FAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEY 71
            |:||....|..:..:|..|::|.:|:|:|||.||||.|:..|:|||.|::.|:::.: .||:.||
  Fly    34 FSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEKRVVS-RSLDKEY 97

Human    72 LPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYV 136
            ..|:|:.||.:.|..||||..|..|..|.....||:.|||||||||.|||:::.|    |..:|:
  Fly    98 ATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFWQG----NREIYI 158

Human   137 SSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDP 201
            .||:|.||.|:|..||. .:..|||:|.:...||..|.:.||:..||.|||:||||||||||:||
  Fly   159 PSPSWGNHVAIFEHAGL-PVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHNPTGVDP 222

Human   202 TPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNE 266
            |.|||::|::::|.|.|:||.|.||||||:|:::|||.|:|.|.::|.:|..||||:||.|||.|
  Fly   223 TLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKNMGLYGE 287

Human   267 RVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRI 331
            |.|..||:..:.|...:|:||::.::|..:||||..||||.|..|:|.:|..:|..:||.|||||
  Fly   288 RAGAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRI 352

Human   332 LTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTK 396
            :.:|::|:..|..|.:...|:||.:|||||.||||.|:||:.|:.:..:||...||::::|:|:|
  Fly   353 IDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSK 417

Human   397 NLDYVATSIHEAVTK 411
            |::|:|.|||: |||
  Fly   418 NVEYLAESIHK-VTK 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GOT1	NP_002070.1	PTZ00376	5..412	CDD:240390	192/405 (47%)
Got2	NP_722745.1	AAT_I	21..431	CDD:450240	190/403 (47%)