DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ing4 and bip2

DIOPT Version :9

Sequence 1:	NP_001355624.1	Gene:	Ing4 / 28019	MGIID:	107307	Length:	249	Species:	Mus musculus
Sequence 2:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster

Alignment Length:	270	Identity:	63/270 - (23%)
Similarity:	93/270 - (34%)	Gaps:	80/270 - (29%)

- Green bases have known domain annotations that are detailed below.

Mouse    41 EIDKLATEYMSSARSLSSEEKLALLRQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLA 105
            :|.||..:....:...||.||     ::.:| ||.|       |..:.:.|. .|..|....:||
  Fly  1151 QIPKLTLKLSGKSTLFSSSEK-----EMTDA-GKLK-------QTTILSSEN-KKRERDNSPELA 1201

Mouse   106 RFE----ADLKEKQIESSDYDSSSS-----------KGKKKGRTQKEKKAARARSKGKNSDEEAP 155
            ||.    ...|.||.|:....:||:           :..:...:|....:|...|...||:..:.
  Fly  1202 RFSPLVTGPPKNKQSETLHLGNSSTAVLPVPSPVAVRAVQLPVSQTSSNSAGWLSNPNNSNTASS 1266

Mouse   156 KAAQKKLKLVR-----------------------------------TSPEYGMPSVTFGSVHPSD 185
            ..:...:.|.:                                   ||.|.........|..||.
  Fly  1267 TLSASSVLLPQQLMLAPHTIMNNFVPAMCNSTGTVSKSGLCSSPPNTSEENANAMQIAESSRPSS 1331

Mouse   186 VLDMPVDPNEPTYC-LCHQVSYGE-MIGCDNPDCSIEWFHFACVGLTTKPRGK--WFCPRC---- 242
            .:|  .:.|....| .|.:|..|. |||||..|.   |:|:.|||:|..|:..  |||..|
  Fly  1332 YVD--AEGNRIWICPACGKVDDGSAMIGCDGCDA---WYHWICVGITFAPKDNDDWFCRVCVTKK 1391

Mouse   243 ---SQERKKK 249
               ..|:||:
  Fly  1392 RIHGSEKKKR 1401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ing4	NP_001355624.1	TNG2	7..245	CDD:227367	60/264 (23%)
		ING_ING4	11..104	CDD:341095	15/62 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	115..163		9/58 (16%)
		Bipartite nuclear localization signal. /evidence=ECO:0000250	127..148		3/20 (15%)
bip2	NP_651923.2	BTP	4..80	CDD:128846
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997	20/47 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900