Protein Alignment AMY2B and Mal-A7

DIOPT Version :10

• Sequence 1: NP_066188.1
• Gene: AMY2B / 280
• HGNCID: 478
• Length: 511
• Species: Homo sapiens
• Sequence 2: NP_610383.1
• Gene: Mal-A7 / 35829
• FlyBaseID: FBgn0033296
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 92/470 - (19%)
• Similarity: 151/470 - (32%)
• Gaps: 161/470 - (34%)

Human    89 GNEDEFRNMVTRCNNVGVRIYVDAVINHMSG--------------------------NAVSAGTS 127
            |..|:||.::.|.|.:.::|.:|.|.||.|.                          ||.:.|.
  Fly   109 GTLDDFRALIKRANELDLKIILDFVPNHSSDENSWFVKSVNREKGYEDYYVWHDGRVNATTGGR- 172

Human   128 STCGSYFNPGSRDFPAVPYSGWDFNDGKCKTGSGDIENYNDATQVRDCRLVGLLDLALEKDYVRS 192
                   .|.|....|...|.|::|:.:       .:.|.....|:..      ||......|..
  Fly   173 -------EPPSNWLQAFRGSAWEWNEKR-------QQYYLHQFAVQQA------DLNYRNPLVVE 217

Human   193 KIAEYMNHLIDIGVAGFRLDASKHMW-----------PGDIKAILDKLHN---LNSNWFPAGSKP 243
            ::...:.:.:|:||||||.||...::           ..::..:.|.:.:   |.|:...  ::|
  Fly   218 QMKRVLRYWLDLGVAGFRCDAVPVLFEIEPDADGQYADEELSGLTDDVDDRKYLKSDLIE--NRP 280

Human   244 FIYQEVIDL---------------GGE-----------PIKSSDYFGNGRVT---EFKYGAKLGT 279
                |.||:               |||           |..:..::|| |.|   ...:...|.|
  Fly   281 ----ETIDMAYQWRVVMDDYQRIHGGETRVLLIETYAPPAYTMQFYGN-RSTAGAHLPFNFNLIT 340

Human   280 VIRKWNGEKMSYLKNWGEGW-GFMPSDRALVFV-DNHDNQRG---HGAGGASILTFWDARLYKMA 339
            |:.. :|.....:|...:.| ..:|:.|...:| .|||.:|.   :|...|..:......|...:
  Fly   341 VLAS-DGVSAGSIKTAVDNWLDNLPAGRTANWVIGNHDQRRAASRYGTANADAMNMLVMVLPGAS 404

Human   340 VGFMLAHPYGFTRVMSSYRWPRQFQNGNDVNDWVGPPNNNGVIKEVTINPDTTCGNDWVCEHRWR 404
            |.:. ....|.|.  ....|       .|..|.....:|:.:.::.|.:|..|
  Fly   405 VTYQ-GEELGMTD--GEISW-------EDTQDPAACNSNSDIYEQFTRDPSRT------------ 447

Human   405 QIRNMVNFRNVVDGQPFTNWYDNGSNQVAFGRGNRGFIVFNNDDWTFSLTLQTGLP-AGTYCDVI 468
                           || .| .||:|.                  .||...:|.|| |..|..:.
  Fly   448 ---------------PF-QW-TNGTNA------------------GFSTASKTWLPLAADYQTLN 477

Human   469 SGDKINGNCTGIKIY 483
            ...:.....:.:|||
  Fly   478 VETEAAAQRSHLKIY 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMY2B	NP_066188.1	AmyAc_bac_euk_AmyA	25..416	CDD:200456	76/400 (19%)
		PLN02447	<85..>155	CDD:215246	21/91 (23%)
		Aamy_C	422..510	CDD:214749	14/63 (22%)
Mal-A7	NP_610383.1	AmyAc_maltase	36..511	CDD:200467	92/470 (20%)