DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zdhhc8 and CG5196

DIOPT Version :9

Sequence 1:	NP_001365948.1	Gene:	Zdhhc8 / 27801	MGIID:	1338012	Length:	775	Species:	Mus musculus
Sequence 2:	NP_650191.1	Gene:	CG5196 / 41522	FlyBaseID:	FBgn0038039	Length:	427	Species:	Drosophila melanogaster

Alignment Length:	227	Identity:	69/227 - (30%)
Similarity:	96/227 - (42%)	Gaps:	60/227 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse    54 LFLFVLA--NFSMATFMDPGVFPRADEDEDKED-DFRAPLYKNVDVRGIQVRMKWCATCHFYRPP 115
            |.|..||  |:.|||...||:.|:....:|.:| .|                :::|..|..|:.|
  Fly    54 LLLSTLATFNYVMATLTGPGLMPKQWHPKDPKDAQF----------------LQYCKKCEGYKAP 102

Mouse   116 RCSHCSVCDNCVEDFDHHCPWVNNCIGRRNYRYFFLFLL-SLSAHMVGVVAF------GL--LYV 171
            |..||..||.||:..||||||:|:|:|..|:.||..||| |:...:.|.|..      |:  .|.
  Fly   103 RSHHCRKCDRCVKKMDHHCPWINHCVGWANHAYFTYFLLFSILGSLQGTVVLCCSFWRGIYRYYY 167

Mouse   172 LNHSEGLGAAHT-----TITMAVMCV--AGLFFIPVIGL---------------TGFHVVLVTRG 214
            |.|    |.||.     |:...:||:  .||....||||               ||..:.:|.:.
  Fly   168 LTH----GLAHLASVQFTLLSIIMCILGMGLAIGVVIGLSMLLFIQLKTIVNNQTGIEIWIVEKA 228

Mouse   215 ---RTTNEQVTGKFRGGVNPFTRGCYGNVEHV 243
               |..|.....:|   :.|:..|...|:..|
  Fly   229 IYRRYRNADCDDEF---LYPYDLGWRANLRLV 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zdhhc8	NP_001365948.1	DHHC	99..224	CDD:396215	50/158 (32%)
CG5196	NP_650191.1	zf-DHHC	89..223	CDD:279823	48/153 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810