Protein Alignment GNAS and Galphaq

DIOPT Version :9

• Sequence 1: XP_016883301.1
• Gene: GNAS / 2778
• HGNCID: 4392
• Length: 1038
• Species: Homo sapiens
• Sequence 2: NP_725192.2
• Gene: Galphaq / 36384
• FlyBaseID: FBgn0004435
• Length: 396
• Species: Drosophila melanogaster
• Alignment Length: 432
• Identity: 154/432 - (35%)
• Similarity: 228/432 - (52%)
• Gaps: 92/432 - (21%)

Human   654 EKRAQKRAEKKRSKLIDKQLQDEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEE 718
            |.:.|||..::    |:|||:.:|.......:|||||.|||||||.:|||||:|.:|::.|
  Fly     8 EAKEQKRINQE----IEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDE---- 64

Human   719 DPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPD 783
                        :|...::.:..|:..|:::::.||..|  .:.....|:....|.::|:    |
  Fly    65 ------------DKRGYIKLVFQNIFMAMQSMIKAMDML--KISYGQGEHSELADLVMSI----D 111

Human   784 FD----FPPEFYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKID----------------- 827
            ::    |...:....|.||:|.|::.||:|..||||.|.|:|:|..:|
  Fly   112 YETVTTFEDPYLNAIKTLWDDAGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRV 176

Human   828 --------------------------VIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMF 866
                                      .|:||||:|::||:||.||.|:||.|..|.:|.:.|.|.
  Fly   177 RVPTTGIIEYPFDLEEIRFSYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMV 241

Human   867 DVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISV 931
            ||||||.||||||.||.:||:|||:||.|.|:.::.|.:..||::|:..||::|....|.:..||
  Fly   242 DVGGQRSERRKWIHCFENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSV 306

Human   932 ILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPE-DATPEPGEDPRVTRAKYFIRDEFLRISTA 995
            ||||||:|||.||::  .|.:.|||||   |..|: ||         :| |:.||...|:.::.
  Fly   307 ILFLNKKDLLEEKIM--YSHLVDYFPE---YDGPQRDA---------IT-AREFILRMFVDLNP- 355

Human   996 SGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYEL 1037
              |.....|.|||||.|||||:.||...:|.|.:..|:::.|
  Fly   356 --DSEKIIYSHFTCATDTENIKLVFCAVKDTIMQNALKEFNL 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNAS	XP_016883301.1	None
Galphaq	NP_725192.2	G-alpha	34..390	CDD:206639	143/395 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810