Protein Alignment GNAO1 and gnao1

DIOPT Version :9

• Sequence 1: NP_066268.1
• Gene: GNAO1 / 2775
• HGNCID: 4389
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_001016995.1
• Gene: gnao1 / 549749
• XenbaseID: XB-GENE-921635
• Length: 354
• Species: Xenopus tropicalis
• Alignment Length: 354
• Identity: 349/354 - (98%)
• Similarity: 350/354 - (98%)
• Gaps: 0/354 - (0%)

Human     1 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGED 65
            |||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||
 Frog     1 MGCTLSAEERAALERSKQIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIHEDGFSGED 65

Human    66 VKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPFSAELLSAMMR 130
            |||||||||||||||||||||||||||||||||||:||||||||||||||||||||.||||||||
 Frog    66 VKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERRADAKMVCDVVSRMEDTEPFSPELLSAMMR 130

Human   131 LWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNL 195
            ||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   131 LWADSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQDILRTRVKTTGIVETHFTFKNL 195

Human   196 HFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFF 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   196 HFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFF 260

Human   261 IDTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTC 325
            |||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   261 IDTSIILFLNKKDLFAEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTC 325

Human   326 ATDTNNIQVVFDAVTDIIIANNLRGCGLY 354
            |||||||||||||||||||||||||||||
 Frog   326 ATDTNNIQVVFDAVTDIIIANNLRGCGLY 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNAO1	NP_066268.1	G-alpha	34..348	CDD:206639	309/313 (99%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		12/12 (100%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	174..182		7/7 (100%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	197..206		8/8 (100%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	266..273		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		4/4 (100%)
gnao1	NP_001016995.1	G-alpha	34..348	CDD:206639	309/313 (99%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	596	1.000	Domainoid score	I2473
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39203
Inparanoid	1	1.050	622	1.000	Inparanoid score	I6179
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54330
OrthoDB	1	1.010	-	-		D163012at32523
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	1	1.000	-	-		oto153180
Panther	1	1.100	-	-	LDO	PTHR10218
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.080