Protein Alignment GNAL and Galphao

DIOPT Version :9

• Sequence 1: NP_892023.1
• Gene: GNAL / 2774
• HGNCID: 4388
• Length: 458
• Species: Homo sapiens
• Sequence 2: NP_523684.2
• Gene: Galphao / 36104
• FlyBaseID: FBgn0001122
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 374
• Identity: 166/374 - (44%)
• Similarity: 225/374 - (60%)
• Gaps: 32/374 - (8%)

Human    82 SAEEREAAKEREAVKEARKVSRGIDRMLRDQKRDLQQTHRLLLLGAGESGKSTIVKQMRILHVNG 146
            |||||.||        ||  ||.|:|.|::......:..:||||||||||||||||||:|:|.:|
  Fly     6 SAEERAAA--------AR--SRLIERNLKEDGIQAAKDIKLLLLGAGESGKSTIVKQMKIIHESG 60

Human   147 FNPEEKKQKILDIRKNVKDAIVTIVSAMSTIIPPVPLANPENQFRSDYIKSIAP-ITDFE-YSQE 209
            |..|:.||....:..|...::|.|:.||.|:  .:..:|.|.:..:..:..:.. :.|.| :|:|
  Fly    61 FTAEDFKQYRPVVYSNTIQSLVAILRAMPTL--SIQYSNNERESDAKMVFDVCQRMHDTEPFSEE 123

Human   210 FFDHVKKLWDDEGVKACFERSNEYQLIDCAQYFLERIDSVSLVDYTPTDQDLLRCRVLTSGIFET 274
            ....:|:||.|.||:.||.|||||||.|.|:|||:.:|.:...||.||:||:||.||.|:||.|.
  Fly   124 LLAAMKRLWQDAGVQECFSRSNEYQLNDSAKYFLDDLDRLGAKDYQPTEQDILRTRVKTTGIVEV 188

Human   275 RFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIYVAACSSYNMVIREDNNTNRLRESLDLFES 339
            .|....:||.:|||||||.||:|||.||.||||||:..|.|.|:.|:.||..|||::|||.||:|
  Fly   189 HFSFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMQESLKLFDS 253

Human   340 IWNNRWLRTISIILFLNKQDMLAEKVLAGKSKIEDYFPEYANYTVPEDATPDAGEDPKVTRAKFF 404
            |.||:|....||||||||:|:..||:  .||.:...||||.       ...:.||.....:|:|.
  Fly   254 ICNNKWFTDTSIILFLNKKDLFEEKI--RKSPLTICFPEYT-------GGQEYGEAAAYIQAQFE 309

Human   405 IRDLFLRISTATGDGKHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLK 453
            .::.    ||:.   :.||  |.|||.||.||:.||:...|:|...:|:
  Fly   310 AKNK----STSK---EIYC--HMTCATDTNNIQFVFDAVTDVIIANNLR 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNAL	NP_892023.1	G_alpha	99..455	CDD:214595	158/357 (44%)
		G-alpha	120..452	CDD:206639	151/333 (45%)
Galphao	NP_523684.2	G-alpha	34..348	CDD:206639	151/333 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D754573at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820