Protein Alignment GNAI3 and Galphaq

DIOPT Version :9

• Sequence 1: NP_006487.1
• Gene: GNAI3 / 2773
• HGNCID: 4387
• Length: 354
• Species: Homo sapiens
• Sequence 2: NP_725192.2
• Gene: Galphaq / 36384
• FlyBaseID: FBgn0004435
• Length: 396
• Species: Drosophila melanogaster
• Alignment Length: 400
• Identity: 181/400 - (45%)
• Similarity: 234/400 - (58%)
• Gaps: 52/400 - (13%)

Human     1 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDE 65
            |.|.||.|.|.....::.|::.||.|...|.:|:||||||.|||||||.:|||:|||..|||:::
  Fly     1 MECCLSEEAKEQKRINQEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDED 65

Human    66 CKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAE-EGVMTPE--LAGVI 127
            .:.|..:|:.|...::.::|:||..|||.:|:...:    :|..|..|.: |.|.|.|  ....|
  Fly    66 KRGYIKLVFQNIFMAMQSMIKAMDMLKISYGQGEHS----ELADLVMSIDYETVTTFEDPYLNAI 126

Human   128 KRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFK 192
            |.||.|.|:|.|:.|.|||||.|||.|||.||||::|..|:||:||:||.||.||||:|..|..:
  Fly   127 KTLWDDAGIQECYDRRREYQLTDSAKYYLKDLDRVAQPAYLPTEQDILRVRVPTTGIIEYPFDLE 191

Human   193 D-------------------------------------------LYFKMFDVGGQRSERKKWIHC 214
            :                                           :.|:|.|||||||||:|||||
  Fly   192 EIRFSYLSDLARIEQADYLPTEQDILRARVPTTGILEYPFDLDGIVFRMVDVGGQRSERRKWIHC 256

Human   215 FEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIK 279
            ||.||:|||.||||:||.:|.|.:..|||.||..||.:|....||..:|:|||||||||.||||.
  Fly   257 FENVTSIIFLVALSEYDQILFESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIM 321

Human   280 RSPLTICYPEYTG-SNTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVI 343
            .|.|...:|||.| ......|..:|...|.|||...: |.||:||||||||:|::.||.||.|.|
  Fly   322 YSHLVDYFPEYDGPQRDAITAREFILRMFVDLNPDSE-KIIYSHFTCATDTENIKLVFCAVKDTI 385

Human   344 IKNNLKECGL 353
            ::|.|||..|
  Fly   386 MQNALKEFNL 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GNAI3	NP_006487.1	G-alpha	34..348	CDD:206639	165/360 (46%)
		G1 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	35..48		11/12 (92%)
		G2 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	173..181		5/7 (71%)
		G3 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	196..205		6/8 (75%)
		G4 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	265..272		6/6 (100%)
		G5 motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01230	324..329		4/4 (100%)
Galphaq	NP_725192.2	G-alpha	34..390	CDD:206639	165/360 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0082
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54330
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000052
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X53
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820