Protein Alignment Dscam4 and ROBO1

DIOPT Version :10

• Sequence 1: NP_001261571.1
• Gene: Dscam4 / 2769008
• FlyBaseID: FBgn0263219
• Length: 1935
• Species: Drosophila melanogaster
• Sequence 2: XP_011532278.1
• Gene: ROBO1 / 6091
• HGNCID: 10249
• Length: 1654
• Species: Homo sapiens
• Alignment Length: 45
• Identity: 12/45 - (26%)
• Similarity: 21/45 - (46%)
• Gaps: 3/45 - (6%)

  Fly    37 SYIMTTSDQDSSMVVLEDVVKGRRLLTRVVRSGAVV---NKSSSK 78
            |.|.||.:..|..:.:.|....||.:.::.|...::   ||..:|
Human   177 SNIDTTIEGTSDDLTVVDAASLRRQIIKLNRRLQLLEEENKERAK 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dscam4	NP_001261571.1	Ig	31..124	CDD:472250	12/45 (27%)
		Ig strand B	50..54	CDD:409353	0/3 (0%)
		Ig strand C	63..66	CDD:409353	0/2 (0%)
		Ig strand E	82..86	CDD:409353
		Ig strand F	102..107	CDD:409353
		Ig strand G	115..119	CDD:409353
		Ig	235..326	CDD:472250
		Ig strand B	253..257	CDD:409353
		Ig strand C	266..270	CDD:409353
		Ig strand E	292..296	CDD:409353
		Ig strand F	306..311	CDD:409353
		Ig strand G	319..322	CDD:409353
		IgC2_3_Dscam	329..417	CDD:409549
		Ig strand A	330..335	CDD:409549
		Ig strand A'	338..342	CDD:409549
		Ig strand B	345..355	CDD:409549
		Ig strand C	360..366	CDD:409549
		Ig strand C'	367..370	CDD:409549
		Ig strand E	383..389	CDD:409549
		Ig strand F	396..404	CDD:409549
		Ig strand G	407..417	CDD:409549
		IgI_4_Dscam	422..516	CDD:409548
		Ig strand A'	430..434	CDD:409548
		Ig strand B	437..446	CDD:409548
		Ig strand C	451..457	CDD:409548
		Ig strand C'	459..462	CDD:409548
		Ig strand D	467..475	CDD:409548
		Ig strand E	479..488	CDD:409548
		Ig strand F	495..503	CDD:409548
		Ig strand G	506..516	CDD:409548
		IgI_5_Dscam	520..607	CDD:409550
		Ig strand A	520..522	CDD:409550
		Ig strand A'	527..531	CDD:409550
		Ig strand B	534..541	CDD:409550
		Ig strand C	548..554	CDD:409550
		Ig strand C'	555..557	CDD:409550
		Ig strand D	564..568	CDD:409550
		Ig strand E	571..577	CDD:409550
		Ig strand F	585..593	CDD:409550
		Ig strand G	597..607	CDD:409550
		Ig	610..703	CDD:472250
		Ig strand B	629..633	CDD:409353
		Ig strand C	643..647	CDD:409353
		Ig strand E	669..673	CDD:409353
		Ig strand F	683..688	CDD:409353
		Ig strand G	696..699	CDD:409353
		IgI_7_Dscam	706..801	CDD:409546
		Ig strand A	706..710	CDD:409546
		Ig strand A'	715..719	CDD:409546
		Ig strand B	722..731	CDD:409546
		Ig strand C	737..743	CDD:409546
		Ig strand C'	749..752	CDD:409546
		Ig strand D	760..763	CDD:409546
		Ig strand E	766..772	CDD:409546
		Ig strand F	779..787	CDD:409546
		Ig strand G	792..801	CDD:409546
		Ig	804..889	CDD:472250
		Ig strand B	822..826	CDD:409353
		Ig strand C	835..839	CDD:409353
		FN3	<850..1254	CDD:442628
		Ig strand F	882..887	CDD:409353
		FN3	906..999	CDD:238020
		fn3	1117..1203	CDD:394996
		FN3	1185..>1580	CDD:442628
FN3	1405..1494	CDD:238020
ROBO1	XP_011532278.1	IgC_1_Robo	68..166	CDD:409490
		Ig strand A	68..72	CDD:409490
		Ig strand A'	75..80	CDD:409490
		Ig strand B	84..92	CDD:409490
		Ig strand C	98..103	CDD:409490
		Ig strand C'	106..108	CDD:409490
		Ig strand D	119..122	CDD:409490
		Ig strand E	125..131	CDD:409490
		Ig strand F	143..151	CDD:409490
		Ig strand G	154..166	CDD:409490
		IgI_2_Robo	173..258	CDD:409389	12/45 (27%)
		Ig strand A	173..176	CDD:409389
		Ig strand A'	178..182	CDD:409389	1/3 (33%)
		Ig strand B	186..193	CDD:409389	1/6 (17%)
		Ig strand C	201..206	CDD:409389	0/4 (0%)
		Ig strand C'	208..211	CDD:409389	0/2 (0%)
		Ig strand D	217..221	CDD:409389	1/3 (33%)
		Ig strand E	223..229	CDD:409389
		Ig strand F	236..244	CDD:409389
		Ig strand G	247..258	CDD:409389
		IgI_3_Robo	265..347	CDD:409390
		Ig strand A	265..268	CDD:409390
		Ig strand A'	270..274	CDD:409390
		Ig strand B	277..286	CDD:409390
		Ig strand C	292..297	CDD:409390
		Ig strand C'	300..303	CDD:409390
		Ig strand D	306..311	CDD:409390
		Ig strand E	312..319	CDD:409390
		Ig strand F	326..334	CDD:409390
		Ig strand G	337..347	CDD:409390
		IgI_4_Robo	355..452	CDD:409391
		Ig strand A	355..359	CDD:409391
		Ig strand A'	361..365	CDD:409391
		Ig strand B	371..379	CDD:409391
		Ig strand C	382..389	CDD:409391
		Ig strand C'	391..394	CDD:409391
		Ig strand D	407..412	CDD:409391
		Ig strand E	414..421	CDD:409391
		Ig strand F	427..436	CDD:409391
		FN3	428..882	CDD:442628
		Ig strand G	438..449	CDD:409391
		IgI_5_Robo	459..545	CDD:409544
		Ig strand A	459..462	CDD:409544
		Ig strand A'	466..469	CDD:409544
		Ig strand B	475..482	CDD:409544
		Ig strand C	488..493	CDD:409544
		Ig strand C'	495..497	CDD:409544
		Ig strand D	504..508	CDD:409544
		Ig strand E	511..516	CDD:409544
		Ig strand F	524..532	CDD:409544
		Ig strand G	535..545	CDD:409544
		FN3	564..650	CDD:238020