DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dscam4 and DIP-delta

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster


Alignment Length:509 Identity:113/509 - (22%)
Similarity:192/509 - (37%) Gaps:124/509 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   286 ITIVSAGLL-------KITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAHLQPQVQTVDV 343
            :|:|...|:       :.|..|:    .:|.::.|      :...:.:..|..|...|.| ||.|
  Fly     4 LTVVKLLLIALNIFPSRFTNRRI----MFLIYMTN------LVTHVMMDEPRFAQPIPNV-TVAV 57

  Fly   344 DKDAQFQCIVSGHPVHDVNWLH-DGKPILRDNRVEILTDPPR-----------LIIKKVQKEDPG 396
            .:||...|:|.....:.|.|:| |.:.||..:| .:::..||           |.:.:..::|.|
  Fly    58 GRDANLPCVVEHLGGYKVAWIHIDRQMILTIHR-HVISRIPRYSITYTDNTWLLHVNQAHQDDRG 121

  Fly   397 MYQCFVSNEWEQIQSTAELQLG--------DASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQF 453
            .|.|.| |....|.....||:.        :::|      |...::....:::.|.|.|.|.|:.
  Fly   122 YYMCQV-NTNPMISQVGYLQVVVPPNILDIESTP------SSVAVRENQNINMTCRADGFPAPKI 179

  Fly   454 TWSL-DGFPIPDSSRFLVGQYVTIHD-DVISHVNISNVKEEDGGEYTCTAQNAI-GKVSHSAKVN 515
            .|.. ||..|....:    :.|.::| ||:.   ::.|...:.|.|.|.|.|.: ..||....::
  Fly   180 IWRREDGEEIAVEKK----KKVLVYDADVLP---LTKVSRNEMGAYLCIATNGVPPSVSKRIILD 237

  Fly   516 IYGLPYIREMPKITGI-SGSDLIVKCPVAGYPIDKIHWERDG-QTLPINRRQRAYNNGT------ 572
            :...|.|....::.|. ||:|:.:.|....:|...|:|..:. ..||..:.:..|...:      
  Fly   238 VEFSPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIYWVYNSVMVLPSKKYKTDYTENSYRAHMK 302

  Fly   573 LIIEQLQRLEDAGTYTCMAQNKQKQT--SRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQI 635
            |.|..|| ..|.|.|.|:::|...:|  |.|..||    |....|.:.:|:...|          
  Fly   303 LTIRNLQ-YGDFGNYRCISKNSLGETEGSIRVYEI----PLPSTPSKQVTHTTVE---------- 352

  Fly   636 LEGDLPVSFRWERNGKPLIGTGNEVFRRL----------DEYSASLVIEHISSDHSGNYTCIASN 690
                       .|....:..:.|:..:.|          |.|..|     .||..||..:..||:
  Fly   353 -----------SRENNIIPSSRNDTTKSLQTDVGYAMKNDLYPGS-----ASSSSSGGSSSAASS 401

  Fly   691 VAGTERFTVPLTV------NVPPKWIL-----------EPKDSSAQAGADVLLH 727
            .:..:...:|..|      ::..|..|           .|.:.:|.:.|.:|||
  Fly   402 SSSMQTSALPGGVAGNSLSSMGSKGSLAIGKSTFYTERPPNEYAASSVAGLLLH 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386 7/46 (15%)
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353 1/2 (50%)
Ig strand E 292..298 CDD:409353 1/12 (8%)
Ig strand F 305..313 CDD:409353 1/7 (14%)
Ig strand G 316..326 CDD:409353 0/9 (0%)
IgC2_3_Dscam 329..417 CDD:409549 29/99 (29%)
Ig strand B 347..351 CDD:409549 1/3 (33%)
Ig strand C 360..364 CDD:409549 1/3 (33%)
Ig strand E 383..387 CDD:409549 3/14 (21%)
Ig strand F 397..402 CDD:409549 2/4 (50%)
Ig strand G 410..413 CDD:409549 0/2 (0%)
IgI_4_Dscam 422..516 CDD:409548 23/96 (24%)
Ig strand B 439..443 CDD:409548 0/3 (0%)
Ig strand C 452..456 CDD:409548 0/3 (0%)
Ig strand E 482..486 CDD:409548 0/3 (0%)
Ig strand F 496..501 CDD:409548 2/4 (50%)
Ig strand G 509..512 CDD:409548 1/2 (50%)
IgI_5_Dscam 520..607 CDD:409550 27/96 (28%)
Ig strand B 536..540 CDD:409550 0/3 (0%)
Ig strand C 549..553 CDD:409550 1/3 (33%)
Ig strand E 571..575 CDD:409550 1/9 (11%)
Ig strand F 586..591 CDD:409550 2/4 (50%)
Ig strand G 600..603 CDD:409550 1/2 (50%)
Ig 610..703 CDD:416386 17/102 (17%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 1/3 (33%)
Ig strand B 627..636 CDD:409353 0/8 (0%)
Ig strand C 641..648 CDD:409353 0/6 (0%)
Ig strand C' 650..652 CDD:409353 0/1 (0%)
Ig strand D 659..664 CDD:409353 0/4 (0%)
Ig strand E 668..675 CDD:409353 1/6 (17%)
Ig strand F 682..690 CDD:409353 2/7 (29%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 8/33 (24%)
Ig strand B 724..728 CDD:409546 3/4 (75%)
Ig strand C 737..741 CDD:409546
Ig strand E 766..770 CDD:409546
Ig strand F 780..785 CDD:409546
Ig strand G 794..797 CDD:409546
Ig 818..904 CDD:416386
putative Ig strand B 820..827 CDD:409353
putative Ig strand C 835..841 CDD:409353
putative Ig strand C' 853..856 CDD:409353
putative Ig strand D 862..866 CDD:409353
putative Ig strand E 868..874 CDD:409353
putative Ig strand F 881..889 CDD:409353
putative Ig strand G 892..902 CDD:409353
FN3 906..999 CDD:238020
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 28/94 (30%)
Ig 145..238 CDD:416386 23/105 (22%)
Ig strand A 145..149 CDD:409353 0/3 (0%)
Ig strand A' 154..159 CDD:409353 2/10 (20%)
Ig strand B 165..172 CDD:409353 1/6 (17%)
Ig strand C 178..183 CDD:409353 1/4 (25%)
Ig strand C' 185..187 CDD:409353 1/1 (100%)
Ig strand D 195..199 CDD:409353 1/3 (33%)
Ig strand E 203..209 CDD:409353 2/8 (25%)
Ig strand F 216..223 CDD:409353 3/6 (50%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 24/91 (26%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 1/6 (17%)
Ig strand C 272..277 CDD:409353 2/4 (50%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 0/3 (0%)
Ig strand E 295..305 CDD:409353 1/9 (11%)
Ig strand F 314..322 CDD:409353 3/7 (43%)
Ig strand G 325..334 CDD:409353 3/8 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.