DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and igsf9bb

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:XP_009293693.1 Gene:igsf9bb / 569554 ZFINID:ZDB-GENE-091112-15 Length:1439 Species:Danio rerio


Alignment Length:993 Identity:226/993 - (22%)
Similarity:357/993 - (35%) Gaps:295/993 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   310 WVNNTAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDN 374
            :|.:.|| ||:.:...|..||..  ||.|                      |.|...|.||  ..
Zfish    32 FVTSRAG-ETVILGCDVVHPLNG--QPYV----------------------VEWFKFGVPI--PF 69

  Fly   375 RVEILTDPPR----------------LIIKKVQKEDPGMYQC-----------FVSNEWEQIQST 412
            .:.....||.                |.|::|:.||.|.|:|           |.:..|..:...
Zfish    70 FINFRFYPPHVDPEYAGRASLHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWVHLTVN 134

  Fly   413 AELQLGDASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDSSRFLVGQYVTIH 477
            |.....|..|:.:      ..:.|.:::|.|.|.|||.|..:|..:|.|:.||:::.|.      
Zfish   135 APPTFTDTPPQYV------EAKEGGSITLSCTAFGNPKPSVSWLREGNPVQDSTKYKVS------ 187

  Fly   478 DDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPK-ITGISGSDLIVKCP 541
            |..::.|:||   .||.|.|||.|.:..|:..|:.::.:.|.|:|...|: ||.....|....|.
Zfish   188 DGSLTLVSIS---REDRGAYTCRAYSEQGEAVHTTRLLVQGPPFIVSPPENITVNISQDAFFTCQ 249

  Fly   542 VAGYPIDKIH---WERDGQTL--PINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRR 601
            ...||.:..:   ||.|....  .:.||.....:|:|||.|: :.||||.|||...|...:....
Zfish   250 AEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQV-KPEDAGKYTCSPSNSLGRPPSA 313

  Fly   602 NVEIQVLVPPKIMPIQAMTNM-----LREGMRAAISCQILEGDLPV-SFRWERNGKPLIGTGNEV 660
            :..:.|..|.:::      ||     :..|:...|.|.: :.:.|| |.:|:::|.||       
Zfish   314 SAYLTVHYPARVI------NMPPVIYVAIGLPGYIRCPV-DANPPVTSVKWKKDGLPL------- 364

  Fly   661 FRRLDEY-------SASLVIEHISSDHSGNYTCIASNVAGT--ERFTVPLTVNVPPKWILEPKDS 716
              |:::|       ..|:.:..::.|..|.|||:..|..||  .....||.:..|||:::.|...
Zfish   365 --RIEKYPGWSQMEDGSIRVSEVTEDSLGTYTCVPYNSLGTMGPSPPAPLVLKDPPKFLVVPGGE 427

  Fly   717 SAQ-AGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGH 780
            ..| ||.::::.|::.|.|.|.|||:|.:| .|...|.       .:.|.|::.||.:|||..|.
Zfish   428 YRQEAGRELVIPCEAEGDPFPNITWRKKVG-KPSRSKH-------NVLPRGSLQFKSLSKEDHGE 484

  Fly   781 FLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQQ 845
            :.|.|.|...|..:....|.:....|...|           |||..:....|   ..|       
Zfish   485 WECVASNVATSITASTHLLVIGTSPHAPAK-----------VHVTVSTTSAN---VSW------- 528

  Fly   846 YLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQPK 910
                  ||.|        ||     |...|                                   
Zfish   529 ------DSSY--------DG-----GFEQT----------------------------------- 539

  Fly   911 NLRINSQQSRSLQLTWSQPFAGNSPIEEYHIYYKQISDIWQNAEH----LTIAGAQTVINIQQLR 971
                                        :.::|..:....|...|    :.:...|..:.:|.|.
Zfish   540 ----------------------------FSVWYGHVVKREQLGPHDWLSMPVPSGQHWLLVQGLE 576

  Fly   972 PAKAYHIRMSAENKLGASEFSEVVQVTTLEEVPSGP-PLAVRAEPKSSTE------IFVTWDAPE 1029
            |..||...:.|:||||...|||||.|.||....|.| ||.:...|:..|.      :.:||..|.
Zfish   577 PETAYQFSVLAQNKLGTGPFSEVVTVNTLVFPISTPEPLVLLTPPRCLTANRTQQGVLLTWIPPA 641

  Fly  1030 R-----DHWNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHV 1089
            .     ||:   ::.:.:|.:..:..:......|                |.:..:|.:...|..
Zfish   642 NHTSPIDHY---IMDFRLGERWDVLDDAIPAGET----------------EILARDLIQEAWYEF 687

  Fly  1090 IVQAYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVF 1154
            .|.|........||..:.|.:.:..|  |||.|...:          :.|.:.|....|     .
Zfish   688 RVMAVMEDLVSEPSNVVGVSSTDYFP--PPEVPDEGL----------ARPVVAGIVATI-----C 735

  Fly  1155 YISVDELYETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTKVGDGMKTKPFYCRTHEDVPS--- 1216
            :::...|:.|      ....:|..:..||........|:.|           :||...:.||   
Zfish   736 FLAAAILFST------LAACFVNKQRRRKLKRRRDPPLSIT-----------HCRKSVETPSSSG 783

  Fly  1217 --APQAIKAI--PASSSK 1230
              :|::|::|  |:.||:
Zfish   784 KISPESIRSIGPPSESSE 801

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386 5/15 (33%)
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353 1/2 (50%)
Ig strand G 316..326 CDD:409353 3/9 (33%)
IgC2_3_Dscam 329..417 CDD:409549 23/114 (20%)
Ig strand B 347..351 CDD:409549 0/3 (0%)
Ig strand C 360..364 CDD:409549 1/3 (33%)
Ig strand E 383..387 CDD:409549 2/19 (11%)
Ig strand F 397..402 CDD:409549 2/15 (13%)
Ig strand G 410..413 CDD:409549 0/2 (0%)
IgI_4_Dscam 422..516 CDD:409548 28/93 (30%)
Ig strand B 439..443 CDD:409548 1/3 (33%)
Ig strand C 452..456 CDD:409548 0/3 (0%)
Ig strand E 482..486 CDD:409548 1/3 (33%)
Ig strand F 496..501 CDD:409548 3/4 (75%)
Ig strand G 509..512 CDD:409548 1/2 (50%)
IgI_5_Dscam 520..607 CDD:409550 27/92 (29%)
Ig strand B 536..540 CDD:409550 0/3 (0%)
Ig strand C 549..553 CDD:409550 0/6 (0%)
Ig strand E 571..575 CDD:409550 2/3 (67%)
Ig strand F 586..591 CDD:409550 3/4 (75%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 26/107 (24%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 2/8 (25%)
Ig strand B 627..636 CDD:409353 2/8 (25%)
Ig strand C 641..648 CDD:409353 4/7 (57%)
Ig strand C' 650..652 CDD:409353 1/1 (100%)
Ig strand D 659..664 CDD:409353 0/4 (0%)
Ig strand E 668..675 CDD:409353 1/6 (17%)
Ig strand F 682..690 CDD:409353 4/7 (57%)
Ig strand G 693..702 CDD:409353 3/10 (30%)
IgI_7_Dscam 706..801 CDD:409546 31/95 (33%)
Ig strand B 724..728 CDD:409546 0/3 (0%)
Ig strand C 737..741 CDD:409546 2/3 (67%)
Ig strand E 766..770 CDD:409546 1/3 (33%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 12/85 (14%)
putative Ig strand B 820..827 CDD:409353 3/6 (50%)
putative Ig strand C 835..841 CDD:409353 1/5 (20%)
putative Ig strand C' 853..856 CDD:409353 1/2 (50%)
putative Ig strand D 862..866 CDD:409353 1/3 (33%)
putative Ig strand E 868..874 CDD:409353 1/5 (20%)
putative Ig strand F 881..889 CDD:409353 0/7 (0%)
putative Ig strand G 892..902 CDD:409353 0/9 (0%)
FN3 906..999 CDD:238020 20/96 (21%)
FN3 1006..1110 CDD:238020 20/115 (17%)
fn3 1117..1203 CDD:394996 14/85 (16%)
FN3 1215..1307 CDD:238020 8/23 (35%)
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
igsf9bbXP_009293693.1 IG_like 30..113 CDD:214653 26/107 (24%)
Ig 41..113 CDD:143165 21/97 (22%)
IG_like 144..223 CDD:214653 28/93 (30%)
IGc2 151..208 CDD:197706 24/65 (37%)
I-set 227..319 CDD:254352 27/92 (29%)
Ig <263..319 CDD:299845 18/56 (32%)
Ig_2 326..414 CDD:290606 25/103 (24%)
IG_like 329..403 CDD:214653 19/83 (23%)
IG_like 424..504 CDD:214653 27/87 (31%)
Ig 440..504 CDD:299845 23/71 (32%)
FN3 509..604 CDD:238020 34/197 (17%)
FN3 620..704 CDD:238020 16/102 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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