DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and lrit3a

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:NP_001122166.1 Gene:lrit3a / 558559 ZFINID:ZDB-GENE-080723-63 Length:636 Species:Danio rerio


Alignment Length:419 Identity:80/419 - (19%)
Similarity:122/419 - (29%) Gaps:180/419 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   705 VPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIF 769
            |.|..:......::..|::|||.|.::|:||||:.|..|                     :|::.
Zfish   250 VKPTVMTSATKITSPLGSNVLLRCDANGFPTPTLLWTTA---------------------DGSVV 293

  Fly   770 FKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPI 834
            ...:.:||.           |.||                                         
Zfish   294 NNTVVQESP-----------GEGV----------------------------------------- 306

  Fly   835 DFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQ 899
              :|.|                             |.:.....:|.|.|.|:|.|..|..|..|.
Zfish   307 --RWSI-----------------------------LSLHSIVFKDAGDYRCKAKNVAGNAEAYIT 340

  Fly   900 LIVQEV----PEQPKNLRINSQQSRSLQLTWSQP-----FAGNSPIEEYHIYYKQISDIWQNAEH 955
            |.|..|    |..|.|:   ::|......|...|     |...|||.                  
Zfish   341 LSVDGVQPTTPFPPINI---TKQPEDQPTTTFTPTKMPLFTSLSPIT------------------ 384

  Fly   956 LTIAGAQTVI-------------NIQQLRPA--KAYHIRMSAENKLGASEFS-----EVVQVTT- 999
            :|.....|.:             .:|:..||  |...::.|...| |:.:.|     |||:.|| 
Zfish   385 ITTRPVMTTMPPLTTRKSPIPGGGVQRSPPAGDKPAKVQQSKNGK-GSIKKSDIRDIEVVEETTE 448

  Fly  1000 -------LEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDH-------WNGILLGYYVGYQM-SLT 1049
                   .|.:||..||.|         ::..:||.:...       ...:||.|.:..|: ::.
Zfish   449 TAVLLWSAEGLPSDTPLTV---------VYFPYDAKDDKETVDTEVGQGKLLLEYLMPNQVYTVC 504

  Fly  1050 PEDKEVNPTQGFSFKTVEVRSHFGGETVL 1078
            ...|.....|...|.|:|:....|...||
Zfish   505 LVTKSSGKEQCVDFSTLEIGGEEGQNKVL 533

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548
Ig strand B 439..443 CDD:409548
Ig strand C 452..456 CDD:409548
Ig strand E 482..486 CDD:409548
Ig strand F 496..501 CDD:409548
Ig strand G 509..512 CDD:409548
IgI_5_Dscam 520..607 CDD:409550
Ig strand B 536..540 CDD:409550
Ig strand C 549..553 CDD:409550
Ig strand E 571..575 CDD:409550
Ig strand F 586..591 CDD:409550
Ig strand G 600..603 CDD:409550
Ig 610..703 CDD:416386
Ig strand A 611..613 CDD:409353
Ig strand A' 620..624 CDD:409353
Ig strand B 627..636 CDD:409353
Ig strand C 641..648 CDD:409353
Ig strand C' 650..652 CDD:409353
Ig strand D 659..664 CDD:409353
Ig strand E 668..675 CDD:409353
Ig strand F 682..690 CDD:409353
Ig strand G 693..702 CDD:409353
IgI_7_Dscam 706..801 CDD:409546 19/94 (20%)
Ig strand B 724..728 CDD:409546 3/3 (100%)
Ig strand C 737..741 CDD:409546 1/3 (33%)
Ig strand E 766..770 CDD:409546 1/3 (33%)
Ig strand F 780..785 CDD:409546 0/4 (0%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 14/85 (16%)
putative Ig strand B 820..827 CDD:409353 0/6 (0%)
putative Ig strand C 835..841 CDD:409353 1/5 (20%)
putative Ig strand C' 853..856 CDD:409353 0/2 (0%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 1/5 (20%)
putative Ig strand F 881..889 CDD:409353 4/7 (57%)
putative Ig strand G 892..902 CDD:409353 4/9 (44%)
FN3 906..999 CDD:238020 23/117 (20%)
FN3 1006..1110 CDD:238020 17/81 (21%)
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
lrit3aNP_001122166.1 LRR_8 81..141 CDD:290566
leucine-rich repeat 83..106 CDD:275378
LRR_4 107..145 CDD:289563
leucine-rich repeat 107..130 CDD:275378
LRR_8 129..>171 CDD:290566
LRR_4 129..170 CDD:289563
leucine-rich repeat 131..154 CDD:275378
leucine-rich repeat 155..168 CDD:275378
TPKR_C2 199..249 CDD:301599
Ig 252..343 CDD:299845 32/194 (16%)
IG_like 261..343 CDD:214653 31/185 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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