DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and Ntm

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:XP_017451354.1 Gene:Ntm / 50864 RGDID:620958 Length:367 Species:Rattus norvegicus


Alignment Length:346 Identity:90/346 - (26%)
Similarity:145/346 - (41%) Gaps:72/346 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   489 VKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDKIHWE 553
            |::.:.....||..|.:.:|   |.:|...:.|          :|:|               .|.
  Rat    47 VRQGESATLRCTIDNRVTRV---AWLNRSTILY----------AGND---------------KWC 83

  Fly   554 RDGQTLPINRRQRAYNNGTLIIEQLQRLE--DAGTYTCMAQ-NKQKQTSRRNVEIQVLVPPKIMP 615
            .|.:.:.::..|..|:     || :|.::  |.|.|||..| :...:|||  |.:.|.|.|||:.
  Rat    84 LDPRVVLLSNTQTQYS-----IE-IQNVDVYDEGPYTCSVQTDNHPKTSR--VHLIV
QVSPKIVE 140

  Fly   616 IQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDH 680
            |.:..: :.||...:::| |..|....:..|.......:|..:|     |||   |.|:.|:.:.
  Rat   141 ISSDIS-INEGNNISLTC-IATGRPEPTVTWRHISPKAVGFVSE-----DEY---LEIQGITREQ 195

  Fly   681 SGNYTCIASN-VAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITW---- 740
            ||.|.|.||| ||......|.:|||.|| :|.|.|.:....|....|.|::|..|:....|    
  Rat   196 SGEYECSASN
DVAAPVVRRVKVTVNYPP-YISEAKGTGVPVGQKGTLQCEASAVPSAEFQWFKDD 259

  Fly   741 KKAIGPTPG---EYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVN 802
            |:.:....|   |.:.||...|          |..:|:...|::.|.|.|.:|...:.::..::|
  Rat   260 KRLVEGKKGVKVENRPFLSRLT----------FFNVSEHDYGNYTCVASNKLGHTNASIMLFELN 314

  Fly   803 VPAHF----QTKTKQISVAKG 819
            .|...    :.||..::..||
  Rat   315 EPTSSTLLQEVKTTALTPWKG 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548 6/26 (23%)
Ig strand B 439..443 CDD:409548
Ig strand C 452..456 CDD:409548
Ig strand E 482..486 CDD:409548
Ig strand F 496..501 CDD:409548 1/4 (25%)
Ig strand G 509..512 CDD:409548 0/2 (0%)
IgI_5_Dscam 520..607 CDD:409550 20/89 (22%)
Ig strand B 536..540 CDD:409550 0/3 (0%)
Ig strand C 549..553 CDD:409550 0/3 (0%)
Ig strand E 571..575 CDD:409550 0/3 (0%)
Ig strand F 586..591 CDD:409550 3/4 (75%)
Ig strand G 600..603 CDD:409550 1/2 (50%)
Ig 610..703 CDD:416386 28/93 (30%)
Ig strand A 611..613 CDD:409353 1/1 (100%)
Ig strand A' 620..624 CDD:409353 0/3 (0%)
Ig strand B 627..636 CDD:409353 1/8 (13%)
Ig strand C 641..648 CDD:409353 1/6 (17%)
Ig strand C' 650..652 CDD:409353 0/1 (0%)
Ig strand D 659..664 CDD:409353 1/4 (25%)
Ig strand E 668..675 CDD:409353 2/6 (33%)
Ig strand F 682..690 CDD:409353 4/7 (57%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 24/101 (24%)
Ig strand B 724..728 CDD:409546 1/3 (33%)
Ig strand C 737..741 CDD:409546 1/7 (14%)
Ig strand E 766..770 CDD:409546 0/3 (0%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 2/2 (100%)
putative Ig strand B 820..827 CDD:409353 90/346 (26%)
putative Ig strand C 835..841 CDD:409353
putative Ig strand C' 853..856 CDD:409353
putative Ig strand D 862..866 CDD:409353
putative Ig strand E 868..874 CDD:409353
putative Ig strand F 881..889 CDD:409353
putative Ig strand G 892..902 CDD:409353
FN3 906..999 CDD:238020
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
NtmXP_017451354.1 Ig 44..132 CDD:416386 27/120 (23%)
Ig strand A' 44..49 CDD:409353 1/1 (100%)
Ig strand B 51..59 CDD:409353 1/7 (14%)
CDR1 59..63 CDD:409353 1/3 (33%)
FR2 64..70 CDD:409353 2/8 (25%)
Ig strand C 64..70 CDD:409353 2/8 (25%)
CDR2 71..83 CDD:409353 3/36 (8%)
Ig strand C' 72..76 CDD:409353 0/3 (0%)
Ig strand C' 80..83 CDD:409353 1/17 (6%)
FR3 84..118 CDD:409353 11/39 (28%)
Ig strand D 87..94 CDD:409353 0/6 (0%)
Ig strand E 97..103 CDD:409353 3/11 (27%)
Ig strand F 110..118 CDD:409353 4/7 (57%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 4/10 (40%)
FR4 125..132 CDD:409353 4/8 (50%)
Ig_3 136..205 CDD:404760 23/78 (29%)
Ig strand A' 144..148 CDD:409353 0/4 (0%)
Ig strand B 151..160 CDD:409353 2/9 (22%)
Ig strand F 197..205 CDD:409353 4/7 (57%)
Ig 223..307 CDD:416386 23/94 (24%)
putative Ig strand A 223..229 CDD:409353 3/6 (50%)
Ig strand B 239..243 CDD:409353 1/3 (33%)
Ig strand C 252..256 CDD:409353 0/3 (0%)
Ig strand E 278..282 CDD:409353 1/13 (8%)
Ig strand F 292..297 CDD:409353 1/4 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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