DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and CG13506

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:NP_001286718.1 Gene:CG13506 / 37556 FlyBaseID:FBgn0034723 Length:503 Species:Drosophila melanogaster


Alignment Length:611 Identity:111/611 - (18%)
Similarity:214/611 - (35%) Gaps:206/611 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   464 DSSR-----FLVGQ-YVTIHDDVISHVNISNVK----EEDGGEYTCTAQNAIGKVSHSAKVNIYG 518
            ||:|     .|:|| ||:.....|.    ::||    ::|..||.....:...::....|.:.. 
  Fly     6 DSTRLLLISLLIGQLYVSCAGSPID----ADVKGTDYQDDEYEYGDDTDDDDTQIIDVTKNHAE- 65

  Fly   519 LPYIREMP--------KITGISGSDLIVKCPVAGYPI-DKIHWER------DGQTLPINRRQRAY 568
                :|.|        ::....|.|:|:.|....:.: :.:.|.:      :||. ||::|.:..
  Fly    66 ----QEAPPYFDVTDLRVEAKPGDDVILNCDARNFQLSNAVVWYKNRIIIANGQN-PISQRVQCM 125

  Fly   569 NNGTLIIEQLQRLEDAGTYTC--MAQNKQKQTSRR-NVEIQVLVPPKIMPIQAMTNMLREGMRAA 630
            .|.::::..:.. ||:..|.|  :.|..::.|:.| ...:.:|...:.:..::.|  .|:|....
  Fly   126 LNNSILLRNVSP-EDSDDYYCEILPQRVRQHTALRVGARLSILCDDRDITDRSQT--FRQGDHHK 187

  Fly   631 ISCQILEGDLP--VSFRW---ERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASN 690
            :.|:..   ||  .:.:|   :.||:|         ..:|..:..::::::...::|:|.|:|.:
  Fly   188 LECRTY---LPDNATIKWSFNDLNGQP---------SSVDNQNGVIILDNVDEKNAGDYQCLADD 240

  Fly   691 VAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFL 755
                                                   .|.:|                     
  Fly   241 ---------------------------------------GSRHP--------------------- 245

  Fly   756 YEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGK 820
                    |:||:                   :|....|.::          .|....::..||.
  Fly   246 --------PHGTV-------------------HIDVQYSPIV----------STHRHNVNTEKGA 273

  Fly   821 QVHVQCNVQGDNPIDFKWKIQ--ATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIY 883
            ...:.||.:. .||...:.|:  .|.|     |..:|:::|.|.:|...:.|.:......|.|.|
  Fly   274 TAELYCNYRA-KPIGRSYFIKDGKTLQ-----LSDKYSLKDSVHNDHNRTTLIVREVTDSDLGEY 332

  Fly   884 ICQASNAFGQDEMSIQLIVQEVPEQP------------------KNLRINSQQSRSLQLTWSQPF 930
            :||..||.|.:|:.:.  |...||.|                  ::.::.|:.....|||.|..:
  Fly   333 LCQVENAIGSNEVKVH--VSYNPETPQFEDMTVEGNKVTLHWLVRSHQLLSEAMLDYQLTGSYTW 395

  Fly   931 AGNSPIEEYHIYYKQISDIWQNAEHLTIAGAQTVINIQQLRPAKAYHIRMSAENKLGASEFS--- 992
            :....:|.:.  :....:||:....|.::..             .:|.|:..:|..|.|.||   
  Fly   396 STVQVLETHR--HNNTDNIWKITHQLELSRG-------------VWHARVKTKNTKGWSHFSNDH 445

  Fly   993 -----EVVQVTTLEEVPSGPPLAVRA 1013
                 |..:|...|||...|...|:|
  Fly   446 VFEIPEDSEVDKDEEVELPPDEIVQA 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548 15/61 (25%)
Ig strand B 439..443 CDD:409548
Ig strand C 452..456 CDD:409548
Ig strand E 482..486 CDD:409548 0/3 (0%)
Ig strand F 496..501 CDD:409548 2/4 (50%)
Ig strand G 509..512 CDD:409548 0/2 (0%)
IgI_5_Dscam 520..607 CDD:409550 20/104 (19%)
Ig strand B 536..540 CDD:409550 1/3 (33%)
Ig strand C 549..553 CDD:409550 0/3 (0%)
Ig strand E 571..575 CDD:409550 0/3 (0%)
Ig strand F 586..591 CDD:409550 2/6 (33%)
Ig strand G 600..603 CDD:409550 1/3 (33%)
Ig 610..703 CDD:416386 15/97 (15%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 1/3 (33%)
Ig strand B 627..636 CDD:409353 1/8 (13%)
Ig strand C 641..648 CDD:409353 2/11 (18%)
Ig strand C' 650..652 CDD:409353 1/1 (100%)
Ig strand D 659..664 CDD:409353 0/4 (0%)
Ig strand E 668..675 CDD:409353 0/6 (0%)
Ig strand F 682..690 CDD:409353 4/7 (57%)
Ig strand G 693..702 CDD:409353 0/8 (0%)
IgI_7_Dscam 706..801 CDD:409546 7/94 (7%)
Ig strand B 724..728 CDD:409546 0/3 (0%)
Ig strand C 737..741 CDD:409546 0/3 (0%)
Ig strand E 766..770 CDD:409546 2/3 (67%)
Ig strand F 780..785 CDD:409546 0/4 (0%)
Ig strand G 794..797 CDD:409546 1/2 (50%)
Ig 818..904 CDD:416386 25/87 (29%)
putative Ig strand B 820..827 CDD:409353 0/6 (0%)
putative Ig strand C 835..841 CDD:409353 0/5 (0%)
putative Ig strand C' 853..856 CDD:409353 0/2 (0%)
putative Ig strand D 862..866 CDD:409353 1/3 (33%)
putative Ig strand E 868..874 CDD:409353 1/5 (20%)
putative Ig strand F 881..889 CDD:409353 4/7 (57%)
putative Ig strand G 892..902 CDD:409353 2/9 (22%)
FN3 906..999 CDD:238020 21/118 (18%)
FN3 1006..1110 CDD:238020 3/8 (38%)
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
CG13506NP_001286718.1 IG_like 79..146 CDD:214653 14/68 (21%)
IGc2 83..146 CDD:197706 14/64 (22%)
IG_like 176..254 CDD:214653 21/178 (12%)
Ig 176..239 CDD:299845 14/76 (18%)
I-set 258..349 CDD:254352 25/108 (23%)
Ig 275..348 CDD:143165 22/78 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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