DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dscam4 and wrapper

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster


Alignment Length:531 Identity:115/531 - (21%)
Similarity:193/531 - (36%) Gaps:110/531 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   537 IVKCPVAGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRR 601
            :|:|.:|...:.::..|.|            :||.                   .:|.||..|  
  Fly     8 VVRCLLAALILGQVQAELD------------FNND-------------------LENSQKFKS-- 39

  Fly   602 NVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSF-RWERNGKPLIGTGNEVFRRLD 665
                   :|..:...:..|        ..:.|.:   :.|..: ||.|:...|:.:.:......|
  Fly    40 -------IPTTVKTYENDT--------VQLPCTL---NTPFRYVRWHRDDVALVDSRHPELPPPD 86

  Fly   666 EY----SASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQ-AGADVL 725
            ..    :.||.:.::.|..:|:|.|..::.:|.......:.|.:.|:.::||.|.:.| .||...
  Fly    87 RIMLWPNGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFE 151

  Fly   726 LHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIG 790
            :.|::.|.|.|.|||:         ....:.:|........::..:..|:...|...|.|.|.:|
  Fly   152 VVCEAQGVPQPVITWR---------LNGNVIQPQSNTGNRQSLILEIKSRNQAGLIECVASNGVG 207

  Fly   791 SGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRY 855
            ......::|.|............:....|.:.|::|.|:.......||    ....|..:|.:..
  Fly   208 EPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKW----FHHGLPVALGAHS 268

  Fly   856 TIRDQVLD-----DGMVSE----LGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQPKN 911
            |..:..|.     |..|:.    |.:......|.|.|.|:|||.......|::|..:.:   |..
  Fly   269 TTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPM---PCL 330

  Fly   912 LRIN--SQQSRSLQLTWSQPFAGNSPIEEYHIYYKQI------SDIWQNAEHLTIAGAQ------ 962
            .:||  :|.|.|..|.|..  ....||.|:.:.::||      ..:..|...|||. ||      
  Fly   331 FKINPGTQSSTSHVLVWQT--ESLLPIMEFKLKFRQIPSNNVTRQVRTNWTELTIP-AQATNGLI 392

  Fly   963 --TVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTW 1025
              |...:..|:||..|.:.:.|.|..|.|:.|::|:..|..||..         |..|||..:..
  Fly   393 YITTYTLHGLQPASLYEVSVLARNSFGWSDNSKIVRFATGGEVEL---------PNYSTESELQD 448

  Fly  1026 DAPERDHWNGI 1036
            |..|.|..|.|
  Fly   449 DFTEEDFHNEI 459

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548
Ig strand B 439..443 CDD:409548
Ig strand C 452..456 CDD:409548
Ig strand E 482..486 CDD:409548
Ig strand F 496..501 CDD:409548
Ig strand G 509..512 CDD:409548
IgI_5_Dscam 520..607 CDD:409550 11/69 (16%)
Ig strand B 536..540 CDD:409550 1/2 (50%)
Ig strand C 549..553 CDD:409550 0/3 (0%)
Ig strand E 571..575 CDD:409550 0/3 (0%)
Ig strand F 586..591 CDD:409550 0/4 (0%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 16/97 (16%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 1/3 (33%)
Ig strand B 627..636 CDD:409353 1/8 (13%)
Ig strand C 641..648 CDD:409353 3/7 (43%)
Ig strand C' 650..652 CDD:409353 0/1 (0%)
Ig strand D 659..664 CDD:409353 0/4 (0%)
Ig strand E 668..675 CDD:409353 2/6 (33%)
Ig strand F 682..690 CDD:409353 3/7 (43%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 22/95 (23%)
Ig strand B 724..728 CDD:409546 0/3 (0%)
Ig strand C 737..741 CDD:409546 2/3 (67%)
Ig strand E 766..770 CDD:409546 0/3 (0%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 22/94 (23%)
putative Ig strand B 820..827 CDD:409353 1/6 (17%)
putative Ig strand C 835..841 CDD:409353 2/5 (40%)
putative Ig strand C' 853..856 CDD:409353 0/2 (0%)
putative Ig strand D 862..866 CDD:409353 2/8 (25%)
putative Ig strand E 868..874 CDD:409353 1/9 (11%)
putative Ig strand F 881..889 CDD:409353 4/7 (57%)
putative Ig strand G 892..902 CDD:409353 2/9 (22%)
FN3 906..999 CDD:238020 30/108 (28%)
FN3 1006..1110 CDD:238020 9/31 (29%)
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
wrapperNP_477404.1 Ig 41..124 CDD:299845 16/93 (17%)
IG_like 41..118 CDD:214653 15/87 (17%)
IG_like 145..218 CDD:214653 17/81 (21%)
Ig 147..219 CDD:299845 17/80 (21%)
I-set 224..323 CDD:254352 21/102 (21%)
IGc2 236..314 CDD:197706 20/81 (25%)
FN3 339..431 CDD:238020 26/94 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.