DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and Opcml

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:XP_006510497.1 Gene:Opcml / 330908 MGIID:97397 Length:354 Species:Mus musculus


Alignment Length:323 Identity:88/323 - (27%)
Similarity:137/323 - (42%) Gaps:48/323 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   340 TVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDN-------RVEILTDPP---RLIIKKVQKED 394
            ||...:.|..:|.:... |..|.||:....:...|       ||.||.:.|   .::|:.|...|
Mouse    46 TVRQGESATLRCTIDDR-VTRVAWLNRSTILYAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYD 109

  Fly   395 PGMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDG 459
            .|.|.|.|..:.....|...| :....|:::...|:.|:..|.:|:|.|:|.|.|.|..||    
Mouse   110 EGPYTCSVQTDNHPKTSRVHL-IVQVPPQIMNISSDITVNEGSSVTLLCLAIGRPEPTVTW---- 169

  Fly   460 FPIPDSSRFL---VGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVS-HSAKVNIYGLP 520
                   |.|   .||.....|:   ::.||::|.:..|||.|:|.|.:.... ...|:.:...|
Mouse   170 -------RHLSVKEGQGFVSEDE---YLEISDIKRDQSGEYECSALNDVAAPDVRKVKITVNYPP 224

  Fly   521 YIREMPKITGIS-GSDLIVKCPVAGYPIDKIHWERDGQTLPIN-RRQRAYNNG---TLIIEQLQR 580
            ||.: .|.||:| |...|:.|..:..|:.:..|.::...|... ...|..|.|   ||....:..
Mouse   225 YISK-AKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATGLDGVRIENKGRISTLTFFNVSE 288

  Fly   581 LEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMT--NMLREGMRA---AISCQILEG 638
             :|.|.|||:|.||...|   |..|.:.   :|.|..|:.  ..:.:|:.:   |::|..|.|
Mouse   289 -KDYGNYTCVATNKLGNT---NASITLY---EISPSSAVAGPGAVIDGVNSASRALACLWLSG 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549 23/86 (27%)
Ig strand B 347..351 CDD:409549 1/3 (33%)
Ig strand C 360..364 CDD:409549 1/3 (33%)
Ig strand E 383..387 CDD:409549 1/6 (17%)
Ig strand F 397..402 CDD:409549 2/4 (50%)
Ig strand G 410..413 CDD:409549 1/2 (50%)
IgI_4_Dscam 422..516 CDD:409548 28/97 (29%)
Ig strand B 439..443 CDD:409548 2/3 (67%)
Ig strand C 452..456 CDD:409548 1/3 (33%)
Ig strand E 482..486 CDD:409548 0/3 (0%)
Ig strand F 496..501 CDD:409548 3/4 (75%)
Ig strand G 509..512 CDD:409548 0/3 (0%)
IgI_5_Dscam 520..607 CDD:409550 29/91 (32%)
Ig strand B 536..540 CDD:409550 1/3 (33%)
Ig strand C 549..553 CDD:409550 0/3 (0%)
Ig strand E 571..575 CDD:409550 3/6 (50%)
Ig strand F 586..591 CDD:409550 3/4 (75%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 8/34 (24%)
Ig strand A 611..613 CDD:409353 0/1 (0%)
Ig strand A' 620..624 CDD:409353 0/5 (0%)
Ig strand B 627..636 CDD:409353 2/11 (18%)
Ig strand C 641..648 CDD:409353
Ig strand C' 650..652 CDD:409353
Ig strand D 659..664 CDD:409353
Ig strand E 668..675 CDD:409353
Ig strand F 682..690 CDD:409353
Ig strand G 693..702 CDD:409353
IgI_7_Dscam 706..801 CDD:409546
Ig strand B 724..728 CDD:409546
Ig strand C 737..741 CDD:409546
Ig strand E 766..770 CDD:409546
Ig strand F 780..785 CDD:409546
Ig strand G 794..797 CDD:409546
Ig 818..904 CDD:416386
putative Ig strand B 820..827 CDD:409353
putative Ig strand C 835..841 CDD:409353
putative Ig strand C' 853..856 CDD:409353
putative Ig strand D 862..866 CDD:409353
putative Ig strand E 868..874 CDD:409353
putative Ig strand F 881..889 CDD:409353
putative Ig strand G 892..902 CDD:409353
FN3 906..999 CDD:238020
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
OpcmlXP_006510497.1 Ig 44..132 CDD:416386 23/87 (26%)
Ig strand A' 44..49 CDD:409353 2/2 (100%)
Ig strand B 51..59 CDD:409353 2/7 (29%)
CDR1 59..63 CDD:409353 0/4 (0%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 1/11 (9%)
Ig strand C' 72..76 CDD:409353 0/3 (0%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 11/33 (33%)
Ig strand D 87..94 CDD:409353 4/6 (67%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 0/3 (0%)
Ig strand G 123..132 CDD:409353 2/9 (22%)
FR4 125..132 CDD:409353 2/7 (29%)
Ig_3 135..206 CDD:404760 26/84 (31%)
Ig strand A 135..138 CDD:409353 1/2 (50%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand C 165..170 CDD:409353 3/15 (20%)
Ig strand C' 171..174 CDD:409353 1/2 (50%)
Ig strand F 198..206 CDD:409353 5/7 (71%)
Ig_3 223..300 CDD:404760 24/78 (31%)
putative Ig strand A 224..230 CDD:409353 3/6 (50%)
Ig strand B 240..244 CDD:409353 1/3 (33%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 2/3 (67%)
Ig strand F 293..298 CDD:409353 3/4 (75%)
Ig strand G 306..309 CDD:409353 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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