DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and Kirrel3

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:XP_038937320.1 Gene:Kirrel3 / 315546 RGDID:1311382 Length:869 Species:Rattus norvegicus


Alignment Length:523 Identity:126/523 - (24%)
Similarity:203/523 - (38%) Gaps:102/523 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   425 LYWFS----EQTLQPGPTVSLKCVATGNPLPQFTWSLDGFP--IPDSSRFLVG-------QYVTI 476
            :|.||    :|.:..|..|:|.|.     :|::    |||.  |.|.....||       ||:.:
  Rat    47 VYSFSQQPQDQVVVSGQPVTLLCA-----IPEY----DGFVLWIKDGLALGVGRDLSSYPQYLVV 102

  Fly   477 --HDDVISHVNISNVKEEDGGEYTCTA-QNAIGKVSHSAKVNIY---GLPYIREMPKITGISGSD 535
              |.....|:.|...:.:|...|.|.| |.||.  |..|::.:.   ..|.|...|.|:..:|..
  Rat   103 GNHLSGEHHLKILRAELQDDAVYECQAIQAAIR--SRPARLTVLVPPDDPIILGGPVISLRAGDP 165

  Fly   536 LIVKCPV-AGYPIDKIHWERDGQTLPINRRQRAYNNGTLIIEQLQR-----------------LE 582
            |.:.|.. ...|...|.|.|.|:.:          ||....:.|.|                 :|
  Rat   166 LNLTCHADNAKPAASIIWLRKGEVI----------NGATYSKTLLRDGKRESIVSTLFISPGDVE 220

  Fly   583 DAGTYTCMAQNKQ----KQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVS 643
            :..:..|.|.||.    |:||   |.|.:..|| ::.:......:.|.......|..........
  Rat   221 NGQSIVCRATNKAIPGGKETS---VTIDIQHPP-LVNLSVEPQPVLEDNIVTFHCSAKANPAVTQ 281

  Fly   644 FRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPK 708
            :||.:.|..:.....|::|...:|:.          .|...:|..:|..|:...:..:.|...|:
  Rat   282 YRWAKRGHIIKEASGELYRTTVDYTY----------FSEPVSCEVTNALGSTNLSRTVDVYFGPR 336

  Fly   709 WILEPKDSSAQAGADVLLHCQSSGYPTPTITW-KKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKK 772
            ...||:......|:|.:..|...|.|:.||.| |:..|              |.|....|:..|.
  Rat   337 MTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSG--------------VVLSNEKTLTLKS 387

  Fly   773 ISKESQGHFLCEA-KNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPID- 835
            :.:|..|.::|.| ...:|:| .:.:.|.||.|....:...|.:: .|::..::|.::...|.| 
  Rat   388 VRQEDAGKYVCRAVVPRVGAG-EREVTLTVNGPPIISSTQTQHAL-HGEKGQIKCFIRSTPPPDR 450

  Fly   836 --FKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQD-TGIYICQASNAFGQDEMS 897
              :.||    :..|:.....|||:.....::|::|.|.||:..|.| ..||.|.|.|:||.|...
  Rat   451 IAWSWK----ENVLESGTSGRYTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEI 511

  Fly   898 IQL 900
            |:|
  Rat   512 IRL 514

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548 30/106 (28%)
Ig strand B 439..443 CDD:409548 2/3 (67%)
Ig strand C 452..456 CDD:409548 0/3 (0%)
Ig strand E 482..486 CDD:409548 1/3 (33%)
Ig strand F 496..501 CDD:409548 2/4 (50%)
Ig strand G 509..512 CDD:409548 1/2 (50%)
IgI_5_Dscam 520..607 CDD:409550 26/108 (24%)
Ig strand B 536..540 CDD:409550 1/3 (33%)
Ig strand C 549..553 CDD:409550 1/3 (33%)
Ig strand E 571..575 CDD:409550 1/3 (33%)
Ig strand F 586..591 CDD:409550 1/4 (25%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 14/92 (15%)
Ig strand A 611..613 CDD:409353 1/1 (100%)
Ig strand A' 620..624 CDD:409353 0/3 (0%)
Ig strand B 627..636 CDD:409353 1/8 (13%)
Ig strand C 641..648 CDD:409353 2/6 (33%)
Ig strand C' 650..652 CDD:409353 1/1 (100%)
Ig strand D 659..664 CDD:409353 2/4 (50%)
Ig strand E 668..675 CDD:409353 0/6 (0%)
Ig strand F 682..690 CDD:409353 1/7 (14%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 24/96 (25%)
Ig strand B 724..728 CDD:409546 0/3 (0%)
Ig strand C 737..741 CDD:409546 3/4 (75%)
Ig strand E 766..770 CDD:409546 1/3 (33%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 27/87 (31%)
putative Ig strand B 820..827 CDD:409353 0/6 (0%)
putative Ig strand C 835..841 CDD:409353 3/8 (38%)
putative Ig strand C' 853..856 CDD:409353 1/2 (50%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 3/5 (60%)
putative Ig strand F 881..889 CDD:409353 4/7 (57%)
putative Ig strand G 892..902 CDD:409353 4/9 (44%)
FN3 906..999 CDD:238020
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
Kirrel3XP_038937320.1 IG_like 54..143 CDD:214653 27/99 (27%)
Ig strand A' 56..60 CDD:409353 1/3 (33%)
Ig strand B 64..71 CDD:409353 3/11 (27%)
Ig strand C 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
Ig strand D 97..101 CDD:409353 2/3 (67%)
Ig strand E 104..116 CDD:409353 3/11 (27%)
Ig strand G 132..143 CDD:409353 4/12 (33%)
IgI_2_KIRREL3-like 149..246 CDD:409416 26/109 (24%)
Ig strand B 166..170 CDD:409416 1/3 (33%)
Ig strand C 180..184 CDD:409416 1/3 (33%)
Ig strand E 210..214 CDD:409416 0/3 (0%)
Ig strand F 224..229 CDD:409416 1/4 (25%)
Ig strand G 239..242 CDD:409416 2/5 (40%)
Ig <267..334 CDD:416386 12/76 (16%)
Ig strand B 267..274 CDD:409353 1/6 (17%)
Ig strand C 279..286 CDD:409353 2/6 (33%)
Ig strand C' 288..291 CDD:409353 1/2 (50%)
Ig strand D 298..302 CDD:409353 1/3 (33%)
Ig strand E 304..310 CDD:409353 1/15 (7%)
Ig strand G 321..334 CDD:409353 2/12 (17%)
Ig 335..416 CDD:416386 24/95 (25%)
Ig strand A' 343..347 CDD:409353 0/3 (0%)
Ig strand B 350..360 CDD:409353 2/9 (22%)
Ig strand C 365..371 CDD:409353 3/5 (60%)
Ig strand E 381..387 CDD:409353 1/5 (20%)
IgI_5_KIRREL3 418..515 CDD:409479 29/102 (28%)
Ig strand B 436..440 CDD:409479 0/3 (0%)
Ig strand C 450..454 CDD:409479 0/3 (0%)
Ig strand E 481..485 CDD:409479 2/3 (67%)
Ig strand F 496..501 CDD:409479 3/4 (75%)
Ig strand G 509..512 CDD:409479 0/2 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 54 1.000 Domainoid score I10917
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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