Sequence 1: | NP_001261571.1 | Gene: | Dscam4 / 2769008 | FlyBaseID: | FBgn0263219 | Length: | 1935 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001380.2 | Gene: | DSCAM / 1826 | HGNCID: | 3039 | Length: | 2012 | Species: | Homo sapiens |
Alignment Length: | 1978 | Identity: | 613/1978 - (30%) |
---|---|---|---|
Similarity: | 949/1978 - (47%) | Gaps: | 230/1978 - (11%) |
- Green bases have known domain annotations that are detailed below.
Fly 2 DLHSLFKAILILYVIRAETSQFVNGLDLQGPIFLHEPPHRVEFSNNSGGLIECSGHGSPPPEVEW 66
Fly 67 TPIPPQQDMVFQL-------SNGSMMFYPFTAEKYRHEVHATVYRCKLRNLVGTVLSREVHVRGV 124
Fly 125 VNQKYAVQVHDEYVMTGNTAVLKCQVPSYMSEFVLVTAWVQDTGMHLYPNTDIGGKYTVLSNGEL 189
Fly 190 YINNAGPNDAYKSYTCRTVNRLTGEVQISTYPGRIIVTEPKGMVQPRINVEKHSMRHVVLNGQTT 254
Fly 255 LPCIAQGHPVPTYRWFKEENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAGEET 319
Fly 320 IQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHPVHDVNWLHDGKPILRDNRVEIL-TDPP 383
Fly 384 RLIIKKVQKEDPGMYQCFVSNEWEQIQSTAELQLGDASPELLYWFSEQTLQPGPTVSLKCVATGN 448
Fly 449 PLPQFTWSLDGFPIPDSSRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAK 513
Fly 514 VNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPINRRQRAY-NNGTLIIEQ 577
Fly 578 LQRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPV 642
Fly 643 SFRWERNGKPLIGTGNEVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPP 707
Fly 708 KWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKK 772
Fly 773 ISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFK 837
Fly 838 WKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIV 902
Fly 903 QEVPEQPKNLRINSQQSRSLQLTWSQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAGAQ----T 963
Fly 964 VINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAP 1028
Fly 1029 ERDHWNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGET-VLANLNKFTQYHVIVQ 1092
Fly 1093 AYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFY-- 1155
Fly 1156 -ISVDELYETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTKVGDGMKTKPFYCRTHEDVPSAPQ 1219
Fly 1220 AIKAIPASSSKIIISWLPPDLPNGDITGYTFY--------MSMLEGGREEGTHKRLLGPFVEMHE 1276
Fly 1277 TVRTQESATYQFWLTASTKMGEGEKTQVVTVPPNNKVPARIVSFSQRIVTPWKEHLELPCRKVGA 1341
Fly 1342 PAPVTIWRQDGHN----METSARKTIAKNGTLYMKECQASDAGNYTCSVENTWGKDEIVYNIVVK 1402
Fly 1403 VPPEAPNLTVINAYTDSLLLEWMDNSHGGSPILGYVINYKRDNGD-WEELQVDSKTTSHLLTNLW 1466
Fly 1467 CGTRYQLYITAYNKIGTGLPCDIVNSYTKGNPPVQPKHSQMITN-NSTSVTCWLDSWGDGGCGIL 1530
Fly 1531 YFMIESRVYGRSSWAVVSNHIPPTERIYTVSDLVPGTKYQLKVTAHNNAGSTTAIYNFTTLSTQG 1595
Fly 1596 ---------VIYNNDHSTPVSHLSDLPFYANFKLLLPICFSLLMLLALIGAALFLRKR------- 1644
Fly 1645 KLASQARLASSSMSESPSLANLQNKQN----------RDQQYLAVRCNPGTSAPRGSNSNDSGSF 1699
Fly 1700 GKAEGNEYIEDICPYATFQLNKQTYSESSYSGNVYSGPYHSVRGSFVYHDVKPESYHSKEPEYTK 1764
Fly 1765 VRRKVG-----------RLRDPH---------------------SESQESD----NPGSTDSEVR 1793
Fly 1794 KILTLHIPITEYDTLGSESDNDVSARALNSAKYRAQ-------------RDTQDE---------T 1836
Fly 1837 SSSSETTP--TSMTRKSKPPFAARKGGK 1862 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Dscam4 | NP_001261571.1 | Ig | 31..124 | CDD:416386 | 20/99 (20%) |
Ig strand A | 32..35 | CDD:409353 | 0/2 (0%) | ||
Ig strand A' | 41..45 | CDD:409353 | 0/3 (0%) | ||
Ig strand B | 48..57 | CDD:409353 | 3/8 (38%) | ||
Ig strand D | 75..78 | CDD:409353 | 0/2 (0%) | ||
Ig strand E | 83..88 | CDD:409353 | 0/4 (0%) | ||
Ig strand F | 101..109 | CDD:409353 | 2/7 (29%) | ||
Ig strand G | 112..124 | CDD:409353 | 4/11 (36%) | ||
Ig | 235..326 | CDD:416386 | 33/90 (37%) | ||
Ig strand A | 235..238 | CDD:409353 | 0/2 (0%) | ||
Ig strand A' | 244..248 | CDD:409353 | 1/3 (33%) | ||
Ig strand B | 251..258 | CDD:409353 | 2/6 (33%) | ||
Ig strand C | 266..271 | CDD:409353 | 3/4 (75%) | ||
Ig strand C' | 276..279 | CDD:409353 | 0/2 (0%) | ||
Ig strand D | 285..289 | CDD:409353 | 1/3 (33%) | ||
Ig strand E | 292..298 | CDD:409353 | 4/5 (80%) | ||
Ig strand F | 305..313 | CDD:409353 | 4/7 (57%) | ||
Ig strand G | 316..326 | CDD:409353 | 2/9 (22%) | ||
IgC2_3_Dscam | 329..417 | CDD:409549 | 23/88 (26%) | ||
Ig strand B | 347..351 | CDD:409549 | 0/3 (0%) | ||
Ig strand C | 360..364 | CDD:409549 | 0/3 (0%) | ||
Ig strand E | 383..387 | CDD:409549 | 1/3 (33%) | ||
Ig strand F | 397..402 | CDD:409549 | 3/4 (75%) | ||
Ig strand G | 410..413 | CDD:409549 | 1/2 (50%) | ||
IgI_4_Dscam | 422..516 | CDD:409548 | 37/93 (40%) | ||
Ig strand B | 439..443 | CDD:409548 | 3/3 (100%) | ||
Ig strand C | 452..456 | CDD:409548 | 1/3 (33%) | ||
Ig strand E | 482..486 | CDD:409548 | 1/3 (33%) | ||
Ig strand F | 496..501 | CDD:409548 | 2/4 (50%) | ||
Ig strand G | 509..512 | CDD:409548 | 0/2 (0%) | ||
IgI_5_Dscam | 520..607 | CDD:409550 | 33/87 (38%) | ||
Ig strand B | 536..540 | CDD:409550 | 0/3 (0%) | ||
Ig strand C | 549..553 | CDD:409550 | 1/3 (33%) | ||
Ig strand E | 571..575 | CDD:409550 | 3/3 (100%) | ||
Ig strand F | 586..591 | CDD:409550 | 3/4 (75%) | ||
Ig strand G | 600..603 | CDD:409550 | 0/2 (0%) | ||
Ig | 610..703 | CDD:416386 | 32/92 (35%) | ||
Ig strand A | 611..613 | CDD:409353 | 1/1 (100%) | ||
Ig strand A' | 620..624 | CDD:409353 | 0/3 (0%) | ||
Ig strand B | 627..636 | CDD:409353 | 3/8 (38%) | ||
Ig strand C | 641..648 | CDD:409353 | 2/6 (33%) | ||
Ig strand C' | 650..652 | CDD:409353 | 1/1 (100%) | ||
Ig strand D | 659..664 | CDD:409353 | 0/4 (0%) | ||
Ig strand E | 668..675 | CDD:409353 | 3/6 (50%) | ||
Ig strand F | 682..690 | CDD:409353 | 7/7 (100%) | ||
Ig strand G | 693..702 | CDD:409353 | 0/8 (0%) | ||
IgI_7_Dscam | 706..801 | CDD:409546 | 32/94 (34%) | ||
Ig strand B | 724..728 | CDD:409546 | 2/3 (67%) | ||
Ig strand C | 737..741 | CDD:409546 | 2/3 (67%) | ||
Ig strand E | 766..770 | CDD:409546 | 1/3 (33%) | ||
Ig strand F | 780..785 | CDD:409546 | 2/4 (50%) | ||
Ig strand G | 794..797 | CDD:409546 | 2/2 (100%) | ||
Ig | 818..904 | CDD:416386 | 24/85 (28%) | ||
putative Ig strand B | 820..827 | CDD:409353 | 0/6 (0%) | ||
putative Ig strand C | 835..841 | CDD:409353 | 1/5 (20%) | ||
putative Ig strand C' | 853..856 | CDD:409353 | 1/2 (50%) | ||
putative Ig strand D | 862..866 | CDD:409353 | 0/3 (0%) | ||
putative Ig strand E | 868..874 | CDD:409353 | 3/5 (60%) | ||
putative Ig strand F | 881..889 | CDD:409353 | 3/7 (43%) | ||
putative Ig strand G | 892..902 | CDD:409353 | 5/9 (56%) | ||
FN3 | 906..999 | CDD:238020 | 34/96 (35%) | ||
FN3 | 1006..1110 | CDD:238020 | 44/104 (42%) | ||
fn3 | 1117..1203 | CDD:394996 | 31/88 (35%) | ||
FN3 | 1215..1307 | CDD:238020 | 25/99 (25%) | ||
Ig | <1334..1401 | CDD:416386 | 25/70 (36%) | ||
Ig strand C | 1345..1349 | CDD:409353 | 0/3 (0%) | ||
Ig strand D | 1363..1366 | CDD:409353 | 1/2 (50%) | ||
Ig strand E | 1367..1372 | CDD:409353 | 1/4 (25%) | ||
Ig strand F | 1380..1388 | CDD:409353 | 3/7 (43%) | ||
Ig strand G | 1394..1401 | CDD:409353 | 3/6 (50%) | ||
FN3 | 1405..1494 | CDD:238020 | 32/89 (36%) | ||
FN3 | 1499..1580 | CDD:238020 | 24/81 (30%) | ||
DSCAM | NP_001380.2 | Ig | 45..113 | CDD:319273 | 14/69 (20%) |
I-set | 235..310 | CDD:254352 | 31/79 (39%) | ||
I-set | 315..385 | CDD:333254 | 16/69 (23%) | ||
Ig_3 | 407..488 | CDD:316449 | 33/80 (41%) | ||
IGc2 | 518..575 | CDD:197706 | 24/56 (43%) | ||
I-set | 596..686 | CDD:333254 | 32/92 (35%) | ||
Ig_DSCAM | 707..784 | CDD:143211 | 26/76 (34%) | ||
Ig | 802..889 | CDD:325142 | 27/89 (30%) | ||
FN3 | 885..978 | CDD:238020 | 34/96 (35%) | ||
FN3 | 986..1083 | CDD:238020 | 44/104 (42%) | ||
FN3 | 1091..1184 | CDD:238020 | 31/94 (33%) | ||
FN3 | 1189..1278 | CDD:238020 | 25/99 (25%) | ||
Ig | 1303..1369 | CDD:319273 | 21/65 (32%) | ||
FN3 | 1380..1470 | CDD:238020 | 32/89 (36%) | ||
FN3 | 1486..1555 | CDD:238020 | 22/70 (31%) | ||
Required for netrin-mediated axon repulsion of neuronal growth cones. /evidence=ECO:0000250|UniProtKB:Q9ERC8 | 1617..2012 | 56/298 (19%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1718..1810 | 16/110 (15%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1855..1883 | 7/27 (26%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1971..2012 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 137 | 1.000 | Domainoid score | I4888 |
eggNOG | 1 | 0.900 | - | - | E1_KOG3510 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 1 | 1.000 | - | - | H74393 | |
Inparanoid | 1 | 1.050 | 968 | 1.000 | Inparanoid score | I322 |
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 1 | 1.010 | - | - | QHG47134 | |
OrthoDB | 1 | 1.010 | - | - | D10185at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0003568 | |
OrthoInspector | 1 | 1.000 | - | - | mtm8541 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_101656 | |
Panther | 1 | 1.100 | - | - | O | PTHR10075 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4969 |
SonicParanoid | 1 | 1.000 | - | - | X1391 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
15 | 14.870 |