DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dscam4 and kirrel1b

DIOPT Version :9

Sequence 1:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster
Sequence 2:XP_017212964.1 Gene:kirrel1b / 100170816 ZFINID:ZDB-GENE-070912-173 Length:801 Species:Danio rerio


Alignment Length:513 Identity:130/513 - (25%)
Similarity:215/513 - (41%) Gaps:88/513 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   429 SEQTLQPGPTVSLKCVA---TGNPLPQFTWSLDGFPIPDSS--------RFL----VGQYVTIHD 478
            ::|::..|..|.|.||.   ||  :.|  |:.||..:....        |.|    ||||     
Zfish    32 ADQSVVIGERVVLSCVVFNYTG--IVQ--WTKDGLALGIGEDLRAWPRYRVLRIMDVGQY----- 87

  Fly   479 DVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIY----GLPYIREMPKITGISGSDLIVK 539
                ::.|::....|...|.|.|..|..: |..||:.:.    | |.|...|:|...:|:...:.
Zfish    88 ----NLEITSADLTDDSLYECQATEAALR-SRRAKLTVLIPPDG-PVIEGSPEILLTAGTSFNLT 146

  Fly   540 CPVAG-YPIDKIHWERDG--------QTLPINRRQRAYNNGTLIIEQLQRLEDAG-TYTCMAQNK 594
            |...| .|:..|.|.:||        .|..::.|:|......|.|:.:.  .|.| .:||:|.|.
Zfish   147 CVSRGAKPMSTIEWYKDGIIVEGAHTSTEVLSDRKRVTTKSFLEIQPMD--TDTGRNFTCVASNL 209

  Fly   595 QKQTSRRN-VEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGN 658
            .....:|: |.:.:..||.:: :......:.||.|...:||.......:.:||.:.|..|.|...
Zfish   210 AAPLGKRSTVTLNIHHPPTVI-LSIEPRSVLEGERVKFTCQATANPPIMGYRWAKGGVILDGARE 273

  Fly   659 EVFRRLDEYSASLVIEHISSDHS---GNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQA 720
            .||             ..::|||   ...:|:..|..|:...::.:.|:..|..::||:..:...
Zfish   274 SVF-------------ETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGPILVVEPRPVTVDV 325

  Fly   721 GADVLLHCQSSGYPTPTITWKKAIGPTPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEA 785
            .:||.|:|:.||.|..|:||.|.             ..::.|..:..:|.|.:|:...|.::|:|
Zfish   326 DSDVTLNCKWSGNPPLTLTWTKK-------------GSSMVLSNSNQLFLKSVSQADAGQYVCKA 377

  Fly   786 -KNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPID---FKWKIQATQQY 846
             ...||.|.::|. |.||.|....::..|.:| :|::..::|.:....|.|   :.||....::.
Zfish   378 IVPRIGVGETEVT-LTVNGPPIISSEPIQYAV-RGEKGEIKCYIASTPPPDKIVWAWKENVWEKE 440

  Fly   847 LDESLDSRYTI---RDQVLDDGMVSELGISHTYRQD-TGIYICQASNAFGQDEMSIQL 900
            ....|: |||:   |.......::|.|.|::....| ...|.|.|.||||...|.|.|
Zfish   441 RGTLLE-RYTVEQSRPATQGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPGTMIITL 497

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549
Ig strand F 397..402 CDD:409549
Ig strand G 410..413 CDD:409549
IgI_4_Dscam 422..516 CDD:409548 27/101 (27%)
Ig strand B 439..443 CDD:409548 2/3 (67%)
Ig strand C 452..456 CDD:409548 1/3 (33%)
Ig strand E 482..486 CDD:409548 0/3 (0%)
Ig strand F 496..501 CDD:409548 2/4 (50%)
Ig strand G 509..512 CDD:409548 1/2 (50%)
IgI_5_Dscam 520..607 CDD:409550 25/97 (26%)
Ig strand B 536..540 CDD:409550 0/3 (0%)
Ig strand C 549..553 CDD:409550 1/3 (33%)
Ig strand E 571..575 CDD:409550 1/3 (33%)
Ig strand F 586..591 CDD:409550 2/4 (50%)
Ig strand G 600..603 CDD:409550 1/3 (33%)
Ig 610..703 CDD:416386 20/95 (21%)
Ig strand A 611..613 CDD:409353 1/1 (100%)
Ig strand A' 620..624 CDD:409353 0/3 (0%)
Ig strand B 627..636 CDD:409353 3/8 (38%)
Ig strand C 641..648 CDD:409353 2/6 (33%)
Ig strand C' 650..652 CDD:409353 1/1 (100%)
Ig strand D 659..664 CDD:409353 2/4 (50%)
Ig strand E 668..675 CDD:409353 0/6 (0%)
Ig strand F 682..690 CDD:409353 1/7 (14%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 26/95 (27%)
Ig strand B 724..728 CDD:409546 2/3 (67%)
Ig strand C 737..741 CDD:409546 2/3 (67%)
Ig strand E 766..770 CDD:409546 0/3 (0%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 25/90 (28%)
putative Ig strand B 820..827 CDD:409353 0/6 (0%)
putative Ig strand C 835..841 CDD:409353 3/8 (38%)
putative Ig strand C' 853..856 CDD:409353 1/2 (50%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 3/5 (60%)
putative Ig strand F 881..889 CDD:409353 3/7 (43%)
putative Ig strand G 892..902 CDD:409353 4/9 (44%)
FN3 906..999 CDD:238020
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
kirrel1bXP_017212964.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 56 1.000 Domainoid score I10962
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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