Protein Alignment CG33234 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_001097483.2
• Gene: CG33234 / 2769006
• FlyBaseID: FBgn0053234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 109/529 - (20%)
• Similarity: 199/529 - (37%)
• Gaps: 152/529 - (28%)

  Fly     1 MSDIDEVFTKLG-FGK--MQFIILLSCFNL---------------------QIWMTN-------- 33
            |:...:|..::| ||:  :|.:|||...|.                     ..|:.|
Human     1 MAQFVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAA 65

  Fly    34 EQLGFGVII----------------AGAS--------------CEM--RIHDRRLAWL------- 59
            |||...|.:                |.||              |:|  ...:.||..|
Human    66 EQLVLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNETQPCDMGWEYPENRLPSLKNEFNLV 130

  Fly    60 ----------MAASFAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLR 114
                      .:...|..:|...::|.|.|..||:..|:....:..::.:.:|.||.|..::.||
Human   131 CDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGLATAFVPSFELYMALR 195

  Fly   115 SVGGFFIAASVVSL----MTYLSEFTKISLRPR--VLTIMSFSLGVSMIYVPCLAGVLLPLRTEP 173
                |.:|.:|..|    :|.|:|:...|.|.:  ||...:|||| .|:    |||:....|
Human   196 ----FAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLG-QMV----LAGLAYGFR--- 248

  Fly   174 SSWRILLLCNQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNSLGVES 238
             :||:|.:....||::.......||||.::.|:....::|:|:::|...:|:.|      |..|.
Human   249 -NWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRK------LSPEL 306

  Fly   239 LTQPRLRQPTEKHGSCYETKVLLLNH---AKIMWFFFIIFF--SLSGLGFALPIWMLRVRVLTAT 298
            :.| .:.:.|...|:..:    |..|   .|:....|.::|  ||...|.:|.:....:.|
Human   307 MNQ-LVPEKTGPSGNALD----LFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDV---- 362

  Fly   299 FTDWDTMCSHLDGIKADSPGRTECHLTYEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVIIGYI 363
                                    :||      .:|.|.|.:.....:..::....|:|..:|.:
Human   363 ------------------------YLT------QLIFGAVEVPARCSSIFMMQRFGRKWSQLGTL 397

  Fly   364 CISIIGCVALNFMEHPNLILISFFAIIDPLICSVRLAGSML--IDLVPTHLRGKVFALISMTGRA 426
            .:..:.|:.:.|:.....::::..|::..:..:.....|.:  .:|.||.||.....|:.:..|.
Human   398 VLGGLMCIIIIFIPADLPVVVTMLAVVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRI 462

  Fly   427 GILITSVYV 435
            |.::|.:.:
Human   463 GGILTPLVI 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	41/164 (25%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	107/518 (21%)
		MFS	139..500	CDD:119392	85/391 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153328
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840