Protein Alignment CG33234 and SLC22A5

DIOPT Version :9

• Sequence 1: NP_001097483.2
• Gene: CG33234 / 2769006
• FlyBaseID: FBgn0053234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001295051.1
• Gene: SLC22A5 / 6584
• HGNCID: 10969
• Length: 581
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 101/457 - (22%)
• Similarity: 183/457 - (40%)
• Gaps: 114/457 - (24%)

  Fly    47 CEMRIHDRRLAWLMAASFAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFL 111
            ||   .|.:....::..|...::..|:.|:|:|.:||:.::.:|..:....|.|......|..|:
Human   160 CE---DDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFV 221

  Fly   112 FLRSVGGFFIAASVVSLMTYLSEF---TKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPL---- 169
            .|      |:...:..:..|::.|   |:| |...|..|.| :|||.:.|  ....::|||
Human   222 VL------FVLVGMGQISNYVAAFVLGTEI-LGKSVRIIFS-TLGVCIFY--AFGYMVLPLFAYF 276

  Fly   170 -RTEPSSWRILLLCNQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNS 233
             |    .||:||:...:||::.:.:..|:||||::.:|....|:|..::.|..:.|
Human   277 IR----DWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKAN--------- 328

  Fly   234 LGV---ESLTQP-RLRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPIWMLRVRV 294
             |:   .::..| .|:..:.|....:....||..                        |.:|: |
Human   329 -GIVVPSTIFDPSELQDLSSKKQQSHNILDLLRT------------------------WNIRM-V 367

  Fly   295 LTATFTDWDTMCSHLDGIKADSPGRTECHLTYEQMTDPMIHG-----CVVLALFVVTSVILTWLS 354
            ...:...|.|:.....|:..|:|.               :||     |.:.|:..|.:.:|.||.
Human   368 TIMSIMLWMTISVGYFGLSLDTPN---------------LHGDIFVNCFLSAMVEVPAYVLAWLL 417

  Fly   355 RRWVIIGYICIS--IIGCVALNFME--HPN-------LILISFFAIIDPLICSVRLAGSML---- 404
            .:::...|...:  .:|...|.||:  .|:       |:::..|        .|..|.||:
Human   418 LQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKF--------GVTAAFSMVYVYT 474

  Fly   405 IDLVPTHLRGKVFALISMTGRAGILITS--VYVGYTLSYICYVTF-NIFILVLIVTGCHVYWLPS 466
            .:|.||.:|.....:.|...|.|.:::.  ||:|....::.|:.. ::.||..|:|    .:||.
Human   475 AELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT----LFLPE 535

  Fly   467 EF 468
            .|
Human   536 SF 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	37/149 (25%)
SLC22A5	NP_001295051.1	2A0119	12..544	CDD:273328	101/457 (22%)
		MFS	162..534	CDD:119392	96/447 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153366
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840