DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and Slc22a21

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_062697.1	Gene:	Slc22a21 / 56517	MGIID:	1929481	Length:	564	Species:	Mus musculus

Alignment Length:	425	Identity:	90/425 - (21%)
Similarity:	167/425 - (39%)	Gaps:	96/425 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 FAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSL 128
            :...::..|:.|:|:|.:||:.|:.:|..:....|.:......|..|..|.::.|....::.|:.
Mouse   150 YVGVLLGSFISGQLSDRFGRKNILFLTMAMHTGFSFIQVFSVNFEMFTLLYTLVGMGHISNYVAA 214

  Fly   129 MTYLSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPL-----RTEPSSWRILLLCNQVPGI 188
            ....:|....|:|     |:..:|||.:.:  ....::|||     |    .||.|||...:||:
Mouse   215 FVLGTEMLSKSVR-----IIFATLGVCIFF--AFGFMVLPLFAYFIR----EWRRLLLAITLPGV 268

  Fly   189 IGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMN--KGKKVTLNSLGVESLTQPRLRQPTEKH 251
            :...:..|:||||::.:|....::|..::.|..::|  .......:......|.....::|...|
Mouse   269 LCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSETNKLQDDSSKKPQSHH 333

  Fly   252 GSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPIWMLR---VRVLT-ATFTDWDTMCSHLDGI 312
              .|:                                ::|   :|:|| .:...|.|:.....|:
Mouse   334 --IYD--------------------------------LVRTPNIRILTIMSIILWLTISVGYFGL 364

  Fly   313 KADSPGRTECHLTYEQMTDPMIHGCVVLALFVVTSVILTWL-----SRRWVIIGYICISIIGCVA 372
            ..|:|          .:...:...|.:||...|.:.:|.||     |||:.:.|.:.:.  |.|.
Mouse   365 SLDTP----------NLNGNIYVNCFLLAAVEVPAYVLAWLLLQHVSRRYSMAGSLFLG--GSVL 417

  Fly   373 LNFMEHPN--------LILISFFAIIDPLICSVRLAGSML----IDLVPTHLRGKVFALISMTGR 425
            |.....|:        |:::..|.|..        |.||:    .:|.||.:|.....:.|...|
Mouse   418 LLVQLVPSDLHYLSTTLVMVGKFGITS--------AYSMVYVYTAELYPTVVRNMGVGVSSTASR 474

  Fly   426 AGILITS--VYVGYTLSYICYVTF-NIFILVLIVT 457
            .|.:::.  ||:|.....:.|:.. ::.||..|:|
Mouse   475 LGSILSPYFVYLGAYDRRLPYILMGSLTILTAIIT 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	33/138 (24%)
Slc22a21	NP_062697.1	2A0119	12..523	CDD:273328	90/425 (21%)
		MFS	123..513	CDD:119392	90/425 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	532..564
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840