DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and SVOP

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_061181.1	Gene:	SVOP / 55530	HGNCID:	25417	Length:	548	Species:	Homo sapiens

Alignment Length:	486	Identity:	121/486 - (24%)
Similarity:	200/486 - (41%)	Gaps:	66/486 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IDEVFTKLGFGKMQFIILLSCFNLQIWMTN--EQLGFGVIIAGASCEMRIHDRRLAWLMAASFAA 66
            :::....:||||.|:  .||......||.:  |.:...::.....||.|:...::|.|.:..|..
Human    70 VEDAVEAIGFGKFQW--KLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVG 132

  Fly    67 QMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSLMTY 131
            .|.|..|||.::|.|||:..:.|:........||||..|.:...|.||.:.||.| ..|...:|.
Human   133 MMSSSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGI-GGVPQSVTL 196

  Fly   132 LSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLCNQVPGIIGIIILVF 196
            .:||..:..|.:.:.::.....:..::...||..::|    ...||.||:.:.||.::..::..:
Human   197 YAEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMP----SLGWRWLLILSAVPLLLFAVLCFW 257

  Fly   197 LPESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNSLGVESLTQPRLRQPTEKHGSCYETKVLL 261
            ||||.:|.:...|||||:..:::|...| |..:.|..|.:.       ||  |..|   :.:.|.
Human   258 LPESARYDVLSGNQEKAIATLKRIATEN-GAPMPLGKLIIS-------RQ--EDRG---KMRDLF 309

  Fly   262 LNHAK----IMWF-FFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSPG-RT 320
            ..|.:    ::|| :|...||..||          |.:.|..|...| :|    ||.:.... ..
Human   310 TPHFRWTTLLLWFIWFSNAFSYYGL----------VLLTTELFQAGD-VC----GISSRKKAVEA 359

  Fly   321 ECHLTYEQMTDPMIHGCVVLALFVVTSVILT-WLSRR----------WVIIGYICISIIGCVALN 374
            :|.|..|.:::......:...|.....|::| |:..|          :||..:..:.:..||..|
Human   360 KCSLACEYLSEEDYMDLLWTTLSEFPGVLVTLWIIDRLGRKKTMALCFVIFSFCSLLLFICVGRN 424

  Fly   375 FMEHPNLILISFFAIIDPLICSVRLAGSMLIDLVPTHLRGKVFALISMTGRAGILITSVYVGYTL 439
            .:   .|:|....|.|..   ..:.|.....::.||..|.......|...|.|.|||.......|
Human   425 VL---TLLLFIARAFISG---GFQAAYVYTPEVYPTATRALGLGTCSGMARVGALITPFIAQVML 483

  Fly   440 SYICYVTFNIF---ILVLIVTGCHVYWLPSE 467
            ....|:|..::   .|:..:..|   :||.|
Human   484 ESSVYLTLAVYSGCCLLAALASC---FLPIE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	38/141 (27%)
SVOP	NP_061181.1	MFS_SVOP	87..509	CDD:340999	112/463 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010