DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and CG31103

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001097914.1	Gene:	CG31103 / 43030	FlyBaseID:	FBgn0051103	Length:	506	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	145/518 - (27%)
Similarity:	231/518 - (44%)	Gaps:	87/518 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DIDEVFTKLGFGKMQFIILLSCFNLQIWMTNEQLGFGVIIAGASCEMRIHDRRLAWLMAASFAAQ 67
            |.|.|..|:|:||.|:::||....|.|.....|....:|:..:.||..........:||||....
  Fly    16 DYDMVLEKIGYGKTQWVLLLVSGLLTITSVAAQQAMSIIVIASQCEFETTQAEKGVMMAASVTGI 80

  Fly    68 MVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSLMTYL 132
            .:|.::||.::|..|||::::..:..:|.:..:...|...|.|..:..:.|..:.|...:|..||
  Fly    81 FLSTYIWGYISDDIGRRRVLLYGNFASNALQFVLMFVTSVWLFNIINLLVGISVGAVSAALYAYL 145

  Fly   133 SEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEPSS-------------WRILLLCNQ 184
            |||.....|...:...:..:.|:.||||..|.::|      ||             ||:|||.:.
  Fly   146 SEFNIPRHRAVAINYSTMFVSVTAIYVPATAWLVL------SSNWAITMGDFVFRPWRLLLLVSL 204

  Fly   185 VPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGKKV---------TLNS------- 233
            :||.||.:||::.|||||:.||.....:|::.:..|.:.|:||.:         ||.|
  Fly   205 LPGFIGGLILLYYPESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFTLKSEDPVGEN 269

  Fly   234 -------LGVES----LTQPRLRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPI 287
                   .|:.|    .|.|...:|   ||..:    :|.|.|     .|.:|||.:|    :.:
  Fly   270 LLGESQGCGILSKICRATIPLFHKP---HGFNF----ILCNLA-----LFGMFFSSNG----MQL 318

  Fly   288 WMLR-VRVLTATFTDWDTMCSHLDGIKADSPGRTE---CHLTYEQMTDP---------MIHGCVV 339
            |... |...:....:..|:|..| .:..:.|..||   |       |||         ::.|...
  Fly   319 WFPEIVNRSSGAENNSSTVCEIL-SVPVEQPNVTETLDC-------TDPISSKTYIDNLVVGFAF 375

  Fly   340 LALFVVTSVILTWLSRRWVIIGYICISIIGCVALNFMEHPN--LILISFFAIIDPLICSVRLAGS 402
            |..|.:..:||..|.|:.|::..:.::.:..|.|:|||.|.  |:|...:.::..|..|:.:..
  Fly   376 LIGFSIQGLILNPLGRKNVLLAALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIMIGA- 439

  Fly   403 MLIDLVPTHLRGKVFALISMTGRAGILITSVYVGYTLSYICYVTFNIFILVLIVTGCHVYWLP 465
             ::||||||||.|..:.....||.||:..:..:|..|...|..||.:|...|||....|::||
  Fly   440 -IVDLVPTHLRSKAVSFCMSLGRLGIIAATNLMGVMLQPYCNTTFAMFTCTLIVCIVIVHYLP 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	44/154 (29%)
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	127/477 (27%)
CG31103	NP_001097914.1	MFS	34..>189	CDD:119392	41/160 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJZM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	1	1.000	-	-		FOG0009986
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900