DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33234 and CG7333

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_650814.2	Gene:	CG7333 / 42334	FlyBaseID:	FBgn0038715	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	560	Identity:	107/560 - (19%)
Similarity:	197/560 - (35%)	Gaps:	173/560 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DIDEVFTKLG-FGKMQFIIL------------------LSCFNLQIWMTNEQL------------ 36
            |..:|..|.| :|:.|.:||                  |..|..:.|..:..|
  Fly     2 DFSQVLDKCGNYGRFQVMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLSVEGIRSVY 66

  Fly    37 ----------------GFGVIIAGASCEMRIHDR---------RLAWLMAAS----------FAA 66
                            |.||:.....|...|.:|         .|.|:...|          |..
  Fly    67 ENISASSCTPLLGVVNGTGVVSTNRKCRNWIFNRESGYESITTELKWVCDKSHHPAVGQSFFFMG 131

  Fly    67 QMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSLMTY 131
            .:|...::|.|:|..||...:::.:........:::.|.....|.|.|.:.|  ::...:..:.|
  Fly   132 SVVGTIIFGYLSDQVGRLPSLLMATLCGATGDFITSFVHTLPWFAFSRFMSG--LSTDTMYYLMY 194

  Fly   132 LSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEP------SSWRILLLCNQVPGIIG 190
            :..|..:|.:.|     :|.|.:.:....|..     |.|.|      .:||..|....:|. :|
  Fly   195 ILVFEYLSPKSR-----TFGLNIILAVFYCFG-----LMTSPWAAIWIGNWRRYLWLASLPA-LG 248

  Fly   191 IIILVFL-PESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNSLGVESLTQPRLRQPTEKHGSC 254
            ::|..|| .||.::.|:....:.|:..::|:.:.|: :.|.      ||:....::...|:....
  Fly   249 VLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNR-RHVE------ESVFDEFVKYYRERELQD 306

  Fly   255 YETKVLLLNHAKIMWFFFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSPGR 319
            |:    |.:|...   |..:|.:.....|.|.: :::..::|.:   .|.:..:::|:
  Fly   307 YK----LNSHEDT---FLAMFLTPRLRRFTLTL-LVKSVIITLS---CDVINRNMEGL------- 353

  Fly   320 TECHLTYEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVII---------GYICISI-IG---CV 371
                            |.....||..||::  :|.....|:         |..|.:: :|   ..
  Fly   354 ----------------GTSPFKLFSFTSIV--YLPAGVAILLLQNKIGRKGMACTALFVGGLITT 400

  Fly   372 ALNFMEHPNLILISFFAIIDP----LICSV-----RLAGSMLID--------LVPTHLRGKVFAL 419
            |..||          .|.:||    |:.::     |...::..|        ::||.:||:..:.
  Fly   401 ATGFM----------IAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSN 455

  Fly   420 ISMTGRAGILITSVYVGYTLSYICYVTF-NIFILVLIVTG 458
            |.:.|.|...: :.||.|...|  |... :|||..|:..|
  Fly   456 IHVIGLASSSL-AFYVIYLAQY--YKPLPSIFISCLMFFG 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	33/158 (21%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	104/551 (19%)
CG7333	NP_650814.2	MFS	126..499	CDD:119392	86/436 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940