Protein Alignment CG33234 and SLC22A25

DIOPT Version :10

• Sequence 1: NP_001097483.2
• Gene: CG33234 / 2769006
• FlyBaseID: FBgn0053234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_955384.3
• Gene: SLC22A25 / 387601
• HGNCID: 32935
• Length: 547
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 92/428 - (21%)
• Similarity: 160/428 - (37%)
• Gaps: 92/428 - (21%)

  Fly    65 AAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSLM 129
            |..||...|:|.|:|.:||:.::..:.....||...:|..|....:..||.:.|....:.:|:.:
Human   154 AGMMVGGNLYGHLSDRFGRKFVLRWSYLQLAIVGTCAAFAPTILVYCSLRFLAGAATFSIIVNTV 218

  Fly   130 TYLSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLCNQVPGIIGIIIL 194
            ..:.|:.........||:...:..:..|.:..||.|:       ....||.|....|..:..:..
Human   219 LLIVEWITHQFCAMALTLTLCAASIGHITLGSLAFVI-------RDQCILQLVMSAPCFVFFLFS 276

  Fly   195 VFLPESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNSLGVE---SLTQPRLRQPTEKHGSCYE 256
            .:|.||.::.:..|..|:.::.:.|....| |.|...:.|.:|   |..:..|....:||..|
Human   277 RWLAESARWLIINNKPEEGLKELRKAAHRN-GMKNAEDILTMEVLKSTMKQELEAAQKKHSLC-- 338

  Fly   257 TKVLLLNH--AKIMWFFFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSPGR 319
             ::|.:.:  .:|.:..|:.|.|      .:|.|.|.:               ||.
Human   339 -ELLRIPNICKRICFLSFVRFAS------TIPFWGLTL---------------HLQ--------- 372

  Fly   320 TECHLTYEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVIIGYICISIIGCVALNFMEHPNLILI 384
               ||.........:.|.|.|....|....|..:|||           :..:.|.|:....|:.|
Human   373 ---HLGNNVFLLQTLFGAVTLLANCVAPWALNHMSRR-----------LSQMLLMFLLATCLLAI 423

  Fly   385 SFFAIIDPLICSVRL--------AGSMLI--------DLVPTHLRGKV------FALISMTGRAG 427
            .|   :...:.::|:        |.|:.|        :|:|:.:||:.      ||.|.....:.
Human   424 IF---VPQEMQTLRVVLATLGVGAASLGITCSTAQENELIPSIIRGRATGITGNFANIGGALASL 485

  Fly   428 ILITSVYVGYTLSYICYVTFNIFILVLIVTGCHVYWLP 465
            ::|.|:| ...|.:|.|..|      .|::|..|..||
Human   486 MMILSIY-SRPLPWIIYGVF------AILSGLVVLLLP 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	2A0119	<64..>234	CDD:273328	37/168 (22%)
SLC22A25	NP_955384.3	MFS_OAT	109..516	CDD:340932	90/426 (21%)