DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_941052.1	Gene:	Slc22a20 / 381203	MGIID:	2685809	Length:	556	Species:	Mus musculus

Alignment Length:	448	Identity:	88/448 - (19%)
Similarity:	162/448 - (36%)	Gaps:	117/448 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 CEMRIHDRRLAWLMAASFAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFL 111
            ||.|.. |.||  .:...:..:|...|:|.|||..||:..::.:.....:....:|.|..|..:.
Mouse   130 CEARTL-RDLA--QSIYMSGVLVGAALFGGLADRLGRKAPLVWSYLQLAVSGAATAYVGSFSAYC 191

  Fly   112 FLRSVGGFFIAASVVSLMTYLSEFTKISLRPR----VLTIMSFSLGVSMIYVPCLAGVLLPLRTE 172
            ..|.:.|...:..:::.::.:.|:  :..|.|    :|...||:||..:     ||||...:|
Mouse   192 VFRFLMGMTFSGIILNSLSLVVEW--MPTRGRTVAGILLGFSFTLGQLI-----LAGVAYLIR-- 247

  Fly   173 PSSWRILLLCNQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMN----KGKKVTLNS 233
              .||.|......|.::..:...:||||.::.|.....::|:|.::|:..||    :|:::|...
Mouse   248 --PWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLQKVAMMNGRKAEGERLTTEV 310

  Fly   234 LGVESLTQPR-------------LRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFAL 285
              |.|..|..             .|.|..:..:|.           :|..:|....:..||...|
Mouse   311 --VSSYIQDEFASVRTSNSILDLFRTPAIRRVTCC-----------LMGVWFSNSVAYYGLAMDL 362

  Fly   286 PIWMLRVRVLTATFTDWDTMCSHLDGIKADSPGRTECHLTYEQMTDPMIHGCVVLALFVVTSVIL 350
            ..:.|.:.::.|.|                                    |.:.:...:|.:..:
Mouse   363 QKFGLSIYLVQALF------------------------------------GIIDIPAMLVATTTM 391

  Fly   351 TWLSRRWVIIGYICISIIGCVALNFMEHPNLILISFFA------IIDPLICSVRLAGSMLIDLVP 409
            .::.||..:..::.::.:..:|..||......|.:..|      :....||.....|    :|.|
Mouse   392 IYVGRRATVSSFLILAGLMVIANMFMPEDLQTLRTVQAALGKGCLASSFICVYLFTG----ELYP 452

  Fly   410 THLRGKVFALISMTGRAGILI---------------------TSVYVGYTLSYICYVT 446
            |.:|.......|:..|.|.|:                     |||..|  ::..|::|
Mouse   453 TEIRQMGMGFASVNARLGGLVAPLITTLGEISPVLPPVSFGATSVLAG--MAVACFLT 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	32/145 (22%)
Slc22a20	NP_941052.1	2A0119	11..518	CDD:273328	88/448 (20%)
		MFS	138..507	CDD:119392	83/436 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..556
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840