DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33234 and Slc22a12

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	XP_038941497.1	Gene:	Slc22a12 / 365398	RGDID:	621628	Length:	578	Species:	Rattus norvegicus

Alignment Length:	443	Identity:	94/443 - (21%)
Similarity:	177/443 - (39%)	Gaps:	121/443 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 MAAS--FAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEF-----WGFLFLRSVG 117
            ||.|  .|..:|...:.|..:|.:|||:::..:..:.::...::|.:|.|     :.||...:|.
  Rat   147 MAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTIAALMPTFPLYCLFRFLVASAVA 211

  Fly   118 GFFI-AASVV-------------------SLMTYLSEFTKISLRPRVLTI--MSFSLGV----SM 156
            |..: .||:.                   ||:..:.|:|.....|.::|:  :.||.|.    |:
  Rat   212 GVMMNTASLCMFPVVLGREGYMQDPELTPSLLLAVMEWTSAQAGPLMMTLNALGFSFGQVLTGSV 276

  Fly   157 IYVPCLAGVLLPLRTEPSSWRILLLCNQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKIC 221
            .|     ||        .|||:|.|....|..:..:...:||||.::.:::...:::::.::::.
  Rat   277 AY-----GV--------RSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGRLDQSLRELQRVA 328

  Fly   222 RMNKGKKVTLNSLGVESL-----TQPRLRQPTEKHGSCYETKVLLLNH--AKIMWFFFIIFFSLS 279
            .:|: :|...::|.||.|     .:|...|...:.|:...|..|.|..  :.:.||.|...|
  Rat   329 AVNR-RKAEADTLTVEVLRSAMQEEPNGNQAGARLGTLLHTPGLRLRTFISMLCWFAFGFTF--- 389

  Fly   280 GLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSP------------GRTECHLTYEQMTDP 332
             .|.||.:..|...:.         :...|.|| .|.|            ||..|     |.:..
  Rat   390 -YGLALDLQALGSNIF---------LLQALIGI-VDLPVKMGSLLLLSRLGRRLC-----QASSL 438

  Fly   333 MIHGCVVLALFVV---TSVILTWLSRRWVIIG-------YICISIIGCVALNFMEHPNLILISFF 387
            ::.|..:||..:|   ..::.:.|:    ::|       :.|::|......     |.:|.::..
  Rat   439 VLPGLCILANILVPREMGILRSSLA----VLGLGSLGAAFTCVTIFSSELF-----PTVIRMTAV 494

  Fly   388 ----------AIIDPLICSVRLAGSMLIDLVPTHLRGKVFALISMTGRAGILI 430
                      |::.||:..:.:.||.|    |..:.|.|..|   :|.|.:|:
  Rat   495 GLGQVAARGGAMLGPLVRLLGVYGSWL----PLLVYGVVPVL---SGLAALLL 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	38/170 (22%)
Slc22a12	XP_038941497.1	MFS_OAT	109..541	CDD:340932	94/443 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346817
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840