DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and CG31106

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_733086.2	Gene:	CG31106 / 318594	FlyBaseID:	FBgn0051106	Length:	513	Species:	Drosophila melanogaster

Alignment Length:	506	Identity:	143/506 - (28%)
Similarity:	247/506 - (48%)	Gaps:	61/506 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DIDEVFTKLGFGKMQFIILLSCFNLQIWMTNEQLGFGVIIAGASCEMRIHDRRLAWLMAASFAAQ 67
            :.::|...:|||::|:|:|.:...|.:.:.||.:|...|...:.|:..::....|.:.||||...
  Fly    25 EYEDVLQIIGFGRVQWIVLFAAGLLLMMVINETMGMSYITIVSQCDFEMNSMDKAVMSAASFIGI 89

  Fly    68 MVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSLMTYL 132
            ..|.:.||.|:|..|||.:::.|:...|.:|:.|..:|.:|.::|:|...|||||.:..:...||
  Fly    90 FCSSYFWGYLSDTIGRRPVLIYTTIAGNFLSLCSTVIPNYWLYVFIRFGVGFFIAGASSTTYAYL 154

  Fly   133 SEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEPS--------SWRILLLCNQVPGII 189
            .||.....||..:...|..:|||.:|||..|.::|.:....|        .||:|.:|..:||::
  Fly   155 GEFFTPRHRPIAINYASLFVGVSTVYVPATAWLILSMDWSVSITDGFSLRPWRLLTICYLLPGVV 219

  Fly   190 GIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGK----------KVTLNSLGVESL----- 239
            |.::|..||||||..:|::..|:|...::.|...|.||          |...|:.|...|
  Fly   220 GTLMLWSLPESPKILMSLHKTEEAFAAVDWIAVTNSGKHLHEFKVHKLKTEDNANGENILLISKS 284

  Fly   240 -----------TQPRLRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPIWMLRVR 293
                       |.|.||:|   |         |||..........:|||.||:|...|  .::.|
  Fly   285 AFTTIKKMWKETLPLLRRP---H---------LLNFVISCTIMCGLFFSSSGMGLWYP--EIQNR 335

  Fly   294 VLTATFTDWDTMC----SHLDGIKADSPGR-TECHLTYEQMTDPMIHGCVVLALFVVTSVILTWL 353
            :.:....|..|:|    :.:|.::|::..: .:.|:..:...|.:.:|..::..:::..:::..:
  Fly   336 LGSNAADDSMTVCQVIDASIDQMQANASNKICDDHINTKSYIDTITYGSALIVGYILMGLVINTI 400

  Fly   354 SRRWVI-IGYICISIIG--CVALNFMEHPNLILISF-FAIIDPLICSVRLAGSMLIDLVPTHLRG 414
            .|:..| ||   :::.|  .:||.|::....|::.| ..::.|.:|...|:|: ::|||||||||
  Fly   401 GRKASISIG---LTLAGACAIALIFIKDEVAIVVCFCLYLVLPGLCVSILSGA-VVDLVPTHLRG 461

  Fly   415 KVFALISMTGRAGILITSVYVGYTLSYICYVTFNIFILVLIVTGCHVYWLP 465
            |...:..|.||.|.:..|..:|..|...|.:||.:|...::|.......||
  Fly   462 KAVCICLMLGRTGSVFGSNIIGVLLESYCSLTFGVFSGFVLVCASLTLLLP 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	50/149 (34%)
CG31106	NP_733086.2	2A0115	37..486	CDD:273327	131/466 (28%)
CG31106	NP_733086.2	MFS	40..512	CDD:119392	136/489 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJZM
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	1	1.000	-	-		FOG0009986
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900