DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and Slc22a15

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001101177.1	Gene:	Slc22a15 / 310732	RGDID:	1311184	Length:	548	Species:	Rattus norvegicus

Alignment Length:	541	Identity:	107/541 - (19%)
Similarity:	198/541 - (36%)	Gaps:	150/541 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DIDEVFT---KLGFGKMQFIILLSCFNLQIWMTNEQLGFGVIIA--------------------- 43
            :::|.|.   ::|..:|....||:.. ||:::..|.:...:|.|
  Rat     2 EVEEAFQAVGEMGLYQMYLCFLLAVL-LQLYVATEAILIALIGATPAYHWDMAELLPNQSHSNQS 65

  Fly    44 ---------------GASCEMRIH------DRRLAWLMAAS------------FAAQMVSCFLWG 75
                           |:.....:|      .....|.:.|:            |:...|....:|
  Rat    66 SGKGQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIANRSYKVSAASSFFFSGVFVGVISFG 130

  Fly    76 ELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSV-----GGFFIAASVVSLMTYLSEF 135
            :|:|.:||:|:.:....:..:.:|.:...|.:..|...|.:     ||..:.|.|:     |:|.
  Rat   131 QLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVL-----LNEC 190

  Fly   136 TKISLRPRVLTI--MSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLCNQVPGIIGIIILVFLP 198
            ...:......:|  :.|::|::..   .|.|..:      .|||.|.:...:.|.:..::.:|:|
  Rat   191 VGAAYWALAGSIGGLFFAVGIAQY---ALLGYFI------RSWRTLAILVNLQGTVVFLLSLFIP 246

  Fly   199 ESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNSLGVESLTQPRLRQPTEKHGS---CYETKVL 260
            |||::..|.....:|.:.:..|.:.|:..|.|.      |||.|..|...|. ||   .:..:|
  Rat   247 ESPRWLYSQGRLSEAEEALYLIAKRNRKLKCTF------SLTHPANRSYRET-GSFLDLFRYRV- 303

  Fly   261 LLNHAKIMWFFFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSPGRTECHLT 325
            ||.|..|:.|   |:|..|.:.:.|        .|:|                .|..|....:|.
  Rat   304 LLGHTLILMF---IWFVCSLVYYGL--------TLSA----------------GDLGGSIYANLA 341

  Fly   326 YEQMTD-PMIHGCVVLALFVVTSVILTWLSRRWVIIGYICISIIGCVALNFMEHPNLILISFFAI 389
            ...:.: |....|:.|       :...|..|:..:..::|:..:.|:.:.|:  |.......||:
  Rat   342 LSGLIEIPSYPLCIYL-------INQRWFGRKRTLAAFLCLGGLACLIVMFL--PEKKDTGVFAV 397

  Fly   390 IDPLICSVRLAGSMLI------------DLVPTHLRGKVFALISMTGRAGILITSVY-----VGY 437
            ::.  .|:.|.|.:.|            :|.||.:|.......||..|.|.:|....     |.:
  Rat   398 VNS--HSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQW 460

  Fly   438 TLSYICY----VTFNIFILVL 454
            :|.:|.:    :|..:..|:|
  Rat   461 SLPFIVFGATGLTSGLLSLLL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	31/160 (19%)
Slc22a15	NP_001101177.1	MFS	111..469	CDD:119392	89/417 (21%)
Slc22a15	NP_001101177.1	MFS_1	111..450	CDD:284993	86/398 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346925
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840