DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33234 and CG3690

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001284764.1	Gene:	CG3690 / 31047	FlyBaseID:	FBgn0040350	Length:	558	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	108/533 - (20%)
Similarity:	214/533 - (40%)	Gaps:	94/533 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDIDEVFTKLGFGKMQFIILLSCFNLQIWMTNEQLGFGVIIAGASCEMRIHDRRLAWLMAASFAA 66
            :|.:......|||....::|::.....:....|......|:..|.|::::.......|.|.::|.
  Fly    30 ADFEAAIDAAGFGMFNILLLVAAVPAAMGTVYETSTMSYILPSAECDLKLSLLDKGILNAITYAG 94

  Fly    67 QMVSCFLWGELADVYGRRKIIMI---TSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSL 128
            .:.|..|||.|||:.|||.::::   ..|:..:...||....:...|.:|   |||.::.....|
  Fly    95 MISSAVLWGYLADIKGRRNLLIVGYAADTICVLGGALSQSRIQLMVFKYL---GGFCMSGPFAVL 156

  Fly   129 MTYLSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLP-------LRTEPSSWRILLLCNQVP 186
            ||||:|......|.|::.::.....::.:.:|.||.::||       .....:||:..:....:|
  Fly   157 MTYLTELHGRKHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALP 221

  Fly   187 GIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGK-------KVTLNSLGV-------E 237
            .::..::..|.|||||:.:|.....:|:...:.:..:|..|       |:..|.:.|       :
  Fly   222 SLLSFVLFFFFPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKD 286

  Fly   238 SLTQPRLRQPTEKHGSCYE-------------------------TKVLLLNHAKIMWFFFIIFFS 277
            ......|:.|||    |.|                         ||..|   ...:|.:.:.|..
  Fly   287 ETIPTELKLPTE----CVEVQDPENQDSKKSSLRSGFTQLRPLFTKPYL---GLSLWVYLLNFCV 344

  Fly   278 LSGLGFALPIWMLRVRVLTATFTDWD----------TMC-----------SHLDGIKADSPGRTE 321
            |.|.. .:.:|:.:   |.|:..:::          ::|           |.|:.:..:.| ..|
  Fly   345 LLGQN-TMRLWLPQ---LFASINEYENLMSGESQSTSICNILEYSVNRTQSQLEAVTRNDP-TVE 404

  Fly   322 CH--LTYEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVIIGYICISIIGC-VALNFMEH--PNL 381
            ||  :|....|:.:|........:::...::..:..:.::...:.|: .|| :.:.:...  ..:
  Fly   405 CHVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKLIMTSGLLIA-AGCSIGMYWSSSAASTV 468

  Fly   382 ILISFFAIIDPLICSVRLAGSMLIDLVPTHLRGKVFALISMTGRAGILITSVYVGYTLSYICYVT 446
            .|.|.|..:..:..:..::.|  :.|.||.||..:.:|..|.||.|.|:.:::....:...|...
  Fly   469 ALASLFVTMGSISATSVISAS--VSLFPTSLRTMIVSLEMMFGRLGSLLGNIFFPALMGLGCVPP 531

  Fly   447 FNIFILVLIVTGC 459
            | :.|...::.||
  Fly   532 F-LMISAFMLAGC 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	38/151 (25%)
CG3690	NP_001284764.1	SP	42..549	CDD:273317	105/521 (20%)
		MFS	49..>195	CDD:119392	37/148 (25%)
		MFS	419..>550	CDD:119392	24/129 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458183
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I296
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	5.000