DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and Slc22a5

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_062142.1	Gene:	Slc22a5 / 29726	RGDID:	3702	Length:	557	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	94/436 - (21%)
Similarity:	168/436 - (38%)	Gaps:	103/436 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 FAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVGGFFIAASVVSL 128
            |...::..|:.|:|:|.:||:.::.:|..:....|.|......|..|..|      |:...:..:
  Rat   150 FVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQLFSVNFEMFTVL------FVLVGMGQI 208

  Fly   129 MTYLSEFT-KISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPL-----RTEPSSWRILLLCNQVPG 187
            ..|::.|. ...:..:.:.|:..:|||.:.|  ....::|||     |    .||:|||...|||
  Rat   209 SNYVAAFVLGTEILSKSIRIIFATLGVCIFY--AFGFMVLPLFAYFIR----DWRMLLLALTVPG 267

  Fly   188 IIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGKKVTLNSLGVESLTQPRLRQPTEKHG 252
            ::...:..|:||||::.:|....::|..::.|..:.| |............|.....::|...|
  Rat   268 VLCGALWWFIPESPRWLISQGRVKEAEVIIRKAAKFN-GIVAPSTIFDPSELQDLNSKKPQSHH- 330

  Fly   253 SCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSP 317
             .|:  ::...:.:|:....||.                          |.|:.....|:..|:|
  Rat   331 -IYD--LVRTRNIRIITIMSIIL--------------------------WLTISVGYFGLSLDTP 366

  Fly   318 GRTECHLTYEQMTDPMIHG-----CVVLALFVVTSVILTW-----LSRRWVIIGYICISIIGCVA 372
            .               :||     |.:||...|.:.:|.|     |.||:.|...:.:.  |.|.
  Rat   367 N---------------LHGDIYVNCFLLAAVEVPAYVLAWLLLQHLPRRYSISAALFLG--GSVL 414

  Fly   373 LNFMEHPN--------LILISFFAIIDPLICSVRLAGSML----IDLVPTHLRGKVFALISMTGR 425
            |.....|:        |:::..|.|..        |.||:    .:|.||.:|.....:.|...|
  Rat   415 LFIQLVPSELFYLSTALVMVGKFGITS--------AYSMVYVYTAELYPTVVRNMGVGVSSTASR 471

  Fly   426 AGILITS--VYVGYTLSYICYVTF-NIFILVLIVTGCHVYWLPSEF 468
            .|.:::.  ||:|....::.|:.. ::.||..|:|    .:.|..|
  Rat   472 LGSILSPYFVYLGAYDRFLPYILMGSLTILTAILT----LFFPESF 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	34/139 (24%)
Slc22a5	NP_062142.1	2A0119	12..520	CDD:273328	94/436 (22%)
		MFS	123..510	CDD:119392	92/431 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	537..557
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346945
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840