DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and Slc22a20

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001381833.1	Gene:	Slc22a20 / 293686	RGDID:	1311460	Length:	556	Species:	Rattus norvegicus

Alignment Length:	456	Identity:	91/456 - (19%)
Similarity:	171/456 - (37%)	Gaps:	133/456 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 CEMRIHDRRLAWLMAASFAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSACVPEFWGFL 111
            ||.|.. |.||  .:...:..:|...|:|.|||..||:..::.:.....:...::|.|..|..:.
  Rat   130 CEARTL-RDLA--QSIYMSGVLVGAALFGSLADRLGRKAPLVWSYLQLAVSGAVTAYVGSFSAYC 191

  Fly   112 FLRSVGGFFIAASVVSLMTYLSEFTKISLRPR----VLTIMSFSLGVSMIYVPCLAGVLLPLRTE 172
            ..|.:.|...:..:::.::.:.|:  :..|.|    :|...||:||..:     ||||...:|
  Rat   192 IFRFLMGMTFSGIILNSLSLVVEW--MPTRGRTVAGILLGFSFTLGQLI-----LAGVAYLIR-- 247

  Fly   173 PSSWRILLLCNQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMN----KGKKVTL-- 231
              .||.|......|.::..:...:||||.::.|.....::|:|.:.|:..||    :|:::|:
  Rat   248 --PWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKVAMMNGRKAEGERLTIEV 310

  Fly   232 ---------------NSLGVESLTQPRLRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLS-- 279
                           ||: ::....|.:|                    |:.....:::||.|
  Rat   311 VSSYIQNEFASVRTSNSI-LDLFRTPGIR--------------------KVTCCLMMVWFSNSVA 354

  Fly   280 --GLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADSPGRTECHLTYEQMTDPMIHGCVVLAL 342
              ||...|..:.|.:.::.|.|                                    |.:.:..
  Rat   355 YYGLAMDLQKFGLSIYLVQALF------------------------------------GIIDIPA 383

  Fly   343 FVVTSVILTWLSRRWVIIGYICISIIGCVALNFMEHPNLILISFFA------IIDPLICSVRLAG 401
            .:|.:..:.::.||..:..::.::.:..:|..|:......|.:..|      :....||.....|
  Rat   384 MLVATTTMIYVGRRATVSSFLVLAGLMVIANMFVPEDLQTLRTVQAALGKGCLASSFICVYLFTG 448

  Fly   402 SMLIDLVPTHLR--GKVFALIS--MTGRAGILI-----------------TSVYVGYTLSYICYV 445
                :|.||.:|  |..||.::  :.|.|..||                 |||..|  ::.||::
  Rat   449 ----ELYPTEIRQMGMGFASVNARLGGLAAPLITTLGEISPVLPPVSFGATSVLAG--MAVICFL 507

  Fly   446 T 446
            |
  Rat   508 T 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	32/145 (22%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	90/454 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840