DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33234 and Slc22a19

DIOPT Version :9

Sequence 1:	NP_001097483.2	Gene:	CG33234 / 2769006	FlyBaseID:	FBgn0053234	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_659034.1	Gene:	Slc22a19 / 207151	MGIID:	2442751	Length:	551	Species:	Mus musculus

Alignment Length:	425	Identity:	89/425 - (20%)
Similarity:	173/425 - (40%)	Gaps:	96/425 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 W-LMAASFAAQMVSCFLW-----------GELADVYGRRKIIMITSTVANIVSILSACV---PEF 107
            | |:..|.|...|:.|::           |.|:|.:| ||:|...|.:.  ::|...||   |.|
Mouse   135 WDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFG-RKLIFTCSLLK--MAITETCVAFAPSF 196

  Fly   108 WGFLFLRSVGGFFIAASVVSLMTYLSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTE 172
            ..:..||.:.|.|.:....:....:.|:|....:..|:.::..:.||..   ..|.|:....|
Mouse   197 LIYCSLRFLSGIFSSTLRTNSALLILEWTSPKFQALVMALIFIASGVGQ---TLLGGLAFAFR-- 256

  Fly   173 PSSWRILLLCNQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNK----GKKVTL-- 231
              :|..|.|...||..:.:|...:|.||.::.:..|..:|:::.::|...:|:    |..:||
Mouse   257 --NWHHLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNRIKNSGDALTLEV 319

  Fly   232 -NSLGVESL----TQPR----LRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPI 287
             .::..|.|    |:|.    .|.|..:...|      ||:..:     |:...||.||
Mouse   320 VKTIMKEELEAAQTKPSPLDLFRTPNLRKRIC------LLSFVR-----FVSVMSLLGL------ 367

  Fly   288 WMLRVRVLTATFTDWDTMCSHLDGIKADSPGRTECHLTYEQMTDPMIHGCVVLALFVVTSVILTW 352
             ::.::.|                  :::....:|           ::|.|.:...|:.:..:.:
Mouse   368 -LINIQYL------------------SNNVFLLQC-----------LYGVVCIPANVLGNFSMNY 402

  Fly   353 LSRRWVIIGYICISIIGCVALNFMEHPNLILISFFAIIDPLICSVRLAGSML--IDLVPTHLRGK 415
            :.||...:.::.:..|..:|:.|:.....||..|.:.:...|.|..:..:::  .:||||.:|..
Mouse   403 MGRRMTQLIFMSVLGISILAVVFLPQEMQILRVFLSTLGGAISSASITSTLVHANELVPTIIRAT 467

  Fly   416 VFALISMTGRAG------ILITSVYVGYTLSYICY 444
            ...::.:.|.||      ::|.:.| ..:|.:|.|
Mouse   468 ALGVVGIAGSAGGALSPLLMILTTY-SASLPWIIY 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	37/154 (24%)
Slc22a19	NP_659034.1	Sugar_tr	11..525	CDD:331684	89/425 (21%)
Slc22a19	NP_659034.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..551
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840