Protein Alignment CG33234 and SLC22A12

DIOPT Version :9

• Sequence 1: NP_001097483.2
• Gene: CG33234 / 2769006
• FlyBaseID: FBgn0053234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_006718493.1
• Gene: SLC22A12 / 116085
• HGNCID: 17989
• Length: 578
• Species: Homo sapiens
• Alignment Length: 478
• Identity: 92/478 - (19%)
• Similarity: 166/478 - (34%)
• Gaps: 161/478 - (33%)

  Fly    39 GVIIAGASCEMRIHDRRLAWLMAASFAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSAC 103
            |:::..|:|                           |..:|.:|||.::..:.....::...:|.
Human   155 GILVGAAAC---------------------------GPASDRFGRRLVLTWSYLQMAVMGTAAAF 192

  Fly   104 VPEFWGFLFLRSVGGFFIAASVVSLMTY-------------------------LSEFTKISLRPR 143
            .|.|..:...|.:..|.:|..:::..|.                         :.|:|....||.
Human   193 APAFPVYCLFRFLLAFAVAGVMMNTGTLRRSLTWRHAGGLHAGSRAEPLGLLAVMEWTAARARPL 257

  Fly   144 VLTI--MSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLCNQVPGIIGIIILVFLPESPKYYLS 206
            |:|:  :.||.|..:     .|.|...:|    .|.:|.|...||..:..:...:|.||.::.|:
Human   258 VMTLNSLGFSFGHGL-----TAAVAYGVR----DWTLLQLVVSVPFFLCFLYSWWLAESARWLLT 313

  Fly   207 INNQEKAMQVMEKICRMN-KG-------KKVTLNSLGVE-SLTQP------RLRQPTEKHGSCYE 256
            ....:..:|.:.::..:| ||       .:|.|:::..| |:.||      .||.|..:..:|..
Human   314 TGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCIS 378

  Fly   257 TKVLLLNHAKIMWF-----FFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADS 316
            |         :.||     ||.:...|..||  ..|::|::.:                |: .|.
Human   379 T---------LCWFAFGFTFFGLALDLQALG--SNIFLLQMFI----------------GV-VDI 415

  Fly   317 PGRTECHLTYEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVIIGYICISIIGCVALNFMEHPNL 381
            |.:.               |.::|         |:.|.||..:...:.::.:..:|...:.|...
Human   416 PAKM---------------GALLL---------LSHLGRRPTLAASLLLAGLCILANTLVPHEMG 456

  Fly   382 ILISFFAIIDPLICSVRLAGSMLI----DLVPTHLRGKVFALISMTGRAGILITSVYVGYTLSYI 442
            .|.|..|::.  :..|..|.:.:.    :|.||.||.....|..|..|.|.::..
Human   457 ALRSALAVLG--LGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGP---------- 509

  Fly   443 CYVTFNIFILVLIVTGCHVYWLP 465
                     ||.:: |.|..|||
Human   510 ---------LVRLL-GVHGPWLP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	29/168 (17%)
SLC22A12	XP_006718493.1	2A0119	11..551	CDD:273328	92/478 (19%)
		MFS	122..541	CDD:119392	92/478 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153232
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840