Protein Alignment CG33234 and SLC22A12

DIOPT Version :10

• Sequence 1: NP_001097483.2
• Gene: CG33234 / 2769006
• FlyBaseID: FBgn0053234
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: XP_006718493.1
• Gene: SLC22A12 / 116085
• HGNCID: 17989
• Length: 578
• Species: Homo sapiens
• Alignment Length: 478
• Identity: 92/478 - (19%)
• Similarity: 166/478 - (34%)
• Gaps: 161/478 - (33%)

  Fly    39 GVIIAGASCEMRIHDRRLAWLMAASFAAQMVSCFLWGELADVYGRRKIIMITSTVANIVSILSAC 103
            |:::..|:|                           |..:|.:|||.::..:.....::...:|.
Human   155 GILVGAAAC---------------------------GPASDRFGRRLVLTWSYLQMAVMGTAAAF 192

  Fly   104 VPEFWGFLFLRSVGGFFIAASVVSLMTY-------------------------LSEFTKISLRPR 143
            .|.|..:...|.:..|.:|..:::..|.                         :.|:|....||.
Human   193 APAFPVYCLFRFLLAFAVAGVMMNTGTLRRSLTWRHAGGLHAGSRAEPLGLLAVMEWTAARARPL 257

  Fly   144 VLTI--MSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLCNQVPGIIGIIILVFLPESPKYYLS 206
            |:|:  :.||.|..:     .|.|...:|    .|.:|.|...||..:..:...:|.||.::.|:
Human   258 VMTLNSLGFSFGHGL-----TAAVAYGVR----DWTLLQLVVSVPFFLCFLYSWWLAESARWLLT 313

  Fly   207 INNQEKAMQVMEKICRMN-KG-------KKVTLNSLGVE-SLTQP------RLRQPTEKHGSCYE 256
            ....:..:|.:.::..:| ||       .:|.|:::..| |:.||      .||.|..:..:|..
Human   314 TGRLDWGLQELWRVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCIS 378

  Fly   257 TKVLLLNHAKIMWF-----FFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDTMCSHLDGIKADS 316
            |         :.||     ||.:...|..||  ..|::|::.:                |: .|.
Human   379 T---------LCWFAFGFTFFGLALDLQALG--SNIFLLQMFI----------------GV-VDI 415

  Fly   317 PGRTECHLTYEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVIIGYICISIIGCVALNFMEHPNL 381
            |.:.               |.::|         |:.|.||..:...:.::.:..:|...:.|...
Human   416 PAKM---------------GALLL---------LSHLGRRPTLAASLLLAGLCILANTLVPHEMG 456

  Fly   382 ILISFFAIIDPLICSVRLAGSMLI----DLVPTHLRGKVFALISMTGRAGILITSVYVGYTLSYI 442
            .|.|..|::.  :..|..|.:.:.    :|.||.||.....|..|..|.|.::..
Human   457 ALRSALAVLG--LGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGAILGP---------- 509

  Fly   443 CYVTFNIFILVLIVTGCHVYWLP 465
                     ||.:: |.|..|||
Human   510 ---------LVRLL-GVHGPWLP 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33234	NP_001097483.2	2A0119	<64..>234	CDD:273328	39/204 (19%)
SLC22A12	XP_006718493.1	MFS_OAT	109..541	CDD:340932	92/478 (19%)