Protein Alignment CG33233 and SLC22A14

DIOPT Version :9

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: XP_006713479.2
• Gene: SLC22A14 / 9389
• HGNCID: 8495
• Length: 675
• Species: Homo sapiens
• Alignment Length: 531
• Identity: 102/531 - (19%)
• Similarity: 180/531 - (33%)
• Gaps: 175/531 - (32%)

  Fly    11 LTIGYGLGQVIIFMVS-------FFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGG 68
            |.:.:.|..:|.|.::       .:||..:...|:...:.:|   |..:|......::   .:.|
Human   216 LPVPWNLDSIIQFGLNDTDTCQDGWIYPDAKKRSLINEFDLV---CGMETKKDTAQIM---FMAG 274

  Fly    69 MVASGLFIGFLADRYGRKFVIRLALVGALSFSVISALMPD-----LYSLSVIRIIVGTFLSAVAS 128
            :....|....:.|:.||...|.|:|:|.:.|...:|.|..     .:...:.:.:||..:|:::.
Human   275 LPIGSLIFRLITDKMGRYPAILLSLLGLIIFGFGTAFMNSFHLYLFFRFGISQSVVGYAISSISL 339

  Fly   129 LQVGFLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFF 193
            .....:||..|              ..:.|.:|.....|:|....      :|:|..|:.|   |
Human   340 ATEWLVGEHRA--------------HAIILGHCFFAVGAVLLTGI------AYSLPHWQLL---F 381

  Fly   194 MIPGWLALVGIC---LVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEE------- 248
            ::.|.|.:..|.   ::||:|.:||...:..:|...|.:...:|:|   .:...|.:|
Human   382 LVGGILVIPFISYIWILPESPRWLMMKGKVKEAKQVLCYAASVNKK---TIPSNLLDELQLPRKK 443

  Fly   249 --KSSTND-------------QEGFWKTVWYEYKLLFSK--------------PHVFKF---FIC 281
              ::|..|             ....|.||.|.|..|..:              |.:.:.   ..|
Human   444 VTRASVLDFCKNRQLCKVTLVMSCVWFTVSYTYFTLSLRMRELGVSVHFRHVVPSIMEVPARLCC 508

  Fly   282 LFLI------FGIFFTSIGLGIWFPVIRNMDNSGSNRLCDLVNNNPTFINHEADDTNGTDSESPK 340
            :||:      :.:..|.:...||               |.|:...|     |.:|  |...:.|:
Human   509 IFLLQQIGRKWSLAVTLLQAIIW---------------CLLLLFLP-----EGED--GLRLKWPR 551

  Fly   341 CNDEMTNLIDPVYYGFTYIGCFILASVLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLIFF 405
            |  ..|.|                             .::.||:.|:...||     ...|.:||
Human   552 C--PATEL-----------------------------KSMTILVLMLREFSL-----AATVTVFF 580

  Fly   406 VLMMVLPGVLIPLATSVLVDCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVTCDVTFNIFN 470
                        |.|:.|   ||..||...|.:|...:..|.:|..|:|.....:
Human   581 ------------LYTAEL---LPTVLRATGLGLVSLASVAGAILSLTIISQTPSL---------- 620

  Fly   471 LCLAICVVLAV 481
            |.:.:|.|||:
Human   621 LPIFLCCVLAI 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	92/488 (19%)
		MFS	23..>208	CDD:119392	37/199 (19%)
		MFS	354..>482	CDD:304372	26/128 (20%)
SLC22A14	XP_006713479.2	2A0119	141..650	CDD:273328	102/531 (19%)
		MFS	270..641	CDD:119392	92/474 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840