Protein Alignment CG33233 and Sv2c

DIOPT Version :9

• Sequence 1: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Sequence 2: NP_083486.1
• Gene: Sv2c / 75209
• MGIID: 1922459
• Length: 727
• Species: Mus musculus
• Alignment Length: 581
• Identity: 124/581 - (21%)
• Similarity: 215/581 - (37%)
• Gaps: 141/581 - (24%)

  Fly     3 AMDVDTALLTIGYGLGQVIIFMVSFFIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLG 67
            |...:..:...|:|..|..:|.|.....|....|....|:  ||.|.|.|      ..:.||..|
Mouse   135 AQQYELIIQECGHGRFQWALFFVLGMALMADGVEVFVVGF--VLPSAETD------LCIPNSGSG 191

  Fly    68 --------GMVASGLFIGFLADRYGRK--FVIRLALVGALSFSVISALMPDLYSLSVIRIIVGTF 122
                    ||:....|.|.|||:.|||  .:|.:::.|..:|  :|:.:.......|.|::.|..
Mouse   192 WLGSIVYLGMMVGAFFWGGLADKVGRKQSLLICMSVNGFFAF--LSSFVQGYGFFLVCRLLSGFG 254

  Fly   123 LSAVASLQVGFLGEFHAIKWRPITVAICSQSQGLALIYCPLVAMAILPN-NFNVDLSSSYNLRVW 186
            :.........:..|..|.:.|...::.......:..||...:|.||:|: .::..:.|:|....|
Mouse   255 IGGAIPTVFSYFAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSW 319

  Fly   187 RFLMMFFMIPGWLALVGICLVPETPHFLMSVNRPDKALLALKWICRMNRKKWEDVDITLSEEKSS 251
            |..::...:|...::|.:..:||:|.||:.|.:.|:|.:.||.|...|.:.....:...:..|..
Mouse   320 RVFVIVCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMILKLIHDTNMRARGQPEKVFTVNKIK 384

  Fly   252 TNDQ----------EGFW--------KT----VWYEYKLLFSKP---HVFKFFICLF-LIFGIFF 290
            |..|          .|.|        :|    :|..:...|:.|   :..|..|..| |.||.:
Mouse   385 TPKQIDELIEIESDTGTWYRRCFVRIRTELYGIWLTFMRCFNYPVRENTIKLTIVWFTLSFGYY- 448

  Fly   291 TSIGLGIWFP-VIRNMD-----------------NSGSN-------------------------- 311
               ||.:||| ||:::.                 |...|
Mouse   449 ---GLSVWFPDVIKHLQSDEYALLTRNVQKDKYANFSINFTMENQIHTGMEYENGRFLGVKFKSV 510

  Fly   312 -------RLCDL-----VN---NNPTFINHEADDTN-----GTDSESPKCN-------DEMTNLI 349
                   :.|..     ||   .|.|||:...|:|:     ..|||...|:       .::|  .
Mouse   511 TFKDSVFKSCTFDDVTSVNTYFKNCTFIDTLFDNTDFEPYKFIDSEFQNCSFLHNKTGCQIT--F 573

  Fly   350 DPVY-----YGFTYIGCF------ILASVLVHWMTRKYVIALHILISMILGISLNIMKQPTVVLI 403
            |..|     |...::|..      |::::|:..:.|..::...:::|   |||...:...|...:
Mouse   574 DDDYSAYWIYFVNFLGTLAVLPGNIVSALLMDRIGRLTMLGGSMVLS---GISCFFLWFGTSESM 635

  Fly   404 FFVLMMVLPGVLIPLATS---VLVDCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVT 461
            ...::.:..|:.|....|   |.|:..|.:.|......:.:|.:...|||:.:.|..:.:|
Mouse   636 MIGMLCLYNGLTISAWNSLDVVTVELYPTDRRATGFGFLNALCKAAAVLGNLIFGSLVSIT 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	117/550 (21%)
		MFS	23..>208	CDD:119392	45/195 (23%)
		MFS	354..>482	CDD:304372	23/117 (20%)
Sv2c	NP_083486.1	synapt_SV2	1..727	CDD:130366	124/581 (21%)
		Interaction with SYT1. /evidence=ECO:0000250	1..57
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..128

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724235at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920